ArticleBioinformation2026
Comparative evaluation of open flap debridement with or without injectable platelet-rich fibrin in chronic periodontitis treatment.
Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
7 authors.
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Abstract
Periodontitis, particularly generalized Stage III Grade B periodontitis with intrabony defects, presents significant challenges in treatment, requiring innovative adjunctive therapies to enhance the effectiveness of conventional treatments such as open flap debridement (OFD). Hence, twenty-four patients were randomized to receive OFD alone or OFD + i-PRF. The results showed significant improvements in clinical parameters and radiographic defect fill at 6 months in i-PRF group. I-PRF demonstrated superior outcomes in probing pocket depth reduction and relative attachment level gain. It offers a promising, biocompatible, cost-effective approach for periodontal regeneration. Thus, the of effect i-PRF's as an adjunct to open flap debridement, showing significant improvements in clinical and radiographic outcomes for Stage III Grade B periodontitis with intrabony defects is reported.
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