Evidence map›Paper›PMID 41960518›Full record

ArticleBioinformation2026

An observational study to compare the treatment outcomes of older and newer antiretroviral regimen in HIV patients.

Lovely Lahare, Shashi Marko, Lily Dubey, Pawan Gupta

Abstract read
In one paragraph

Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lovely LahareDepartment of Pharmacology, Bundelkhand Medical College, Sagar, Madhya Pradesh, India.
Shashi MarkoDepartment of Pharmacology, Bundelkhand Medical College, Sagar, Madhya Pradesh, India.
Lily DubeyDepartment of Pharmacology, Bundelkhand Medical College, Sagar, Madhya Pradesh, India.
Pawan GuptaDepartment of Dermatology, Bundelkhand Medical College, Sagar, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The need to compare the effectiveness and adverse effects of Dolutegravir-based regimens versus older TLE regimens in HIV treatment is relevant. Therefore, it is of interest to evaluate their comparative outcomes in a clinical setting including 180 adults with HIV. Results showed comparable efficacy in CD4 counts and viral load between the two groups, although Dolutegravir seemed to cause a quicker increase in CD4 counts. This study contributes to the existing body of knowledge by providing direct comparisons of Dolutegravir-based and older TLE regimens in HIV treatment, highlighting both efficacy and safety outcomes, with a specific focus on CD4 count progression and adverse effects.

Indexed as

antiretroviral therapyCD4 countDolutegravirviral load

Identifiers

PMID41960518
PMCPMC13058344

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.