ArticleBioinformation2026
Comparative evaluation of tissue adhesives and conventional sutures in periodontal flap surgery: A randomized clinical study.
Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Post-surgical discomfort, delayed soft tissue healing and risk of infection remain significant challenges associated with conventional suturing methods in periodontal flap surgeries. Therefore, it is of interest to evaluate four different groups (n=10 each); Group 1 - silk sutures, Group 2 - vicryl sutures, Group 3 - fibrin sealant (Tisseel) and Group 4 - isoepoxy 2-cyanoacrylate adhesives (Amcrylate) and compared effects on wound healing, postoperative discomfort and clinical outcomes in periodontitis patients. Phase I therapy was followed by full-thickness mucoperiosteal flaps elevation, debridement and closure conducted as specified. The measurement of healing was done at 1, 2, 4 and 12 weeks by the use of Landry Healing Index, Visual Analog Scale (VAS) of pain, Plaque and Gingival Indices, Probing Pocket Depth (PPD) and Clinical Attachment Level (CAL). Tissue glues, especially fibrin-based sealants, provided periodontal flap closure with clinically reliable, biocompatible and patient-friendly option which enhances faster hemostatic and early healing.
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