Serum lipid profile patterns in patients with oral cancer and oral potentially malignant disorders.

Priyanka Singh, Sangeeta Gupta, Gaurav Gupta, Deepika Patidar, Dinesh Patidar, Ishita Gupta

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Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Priyanka SinghDepartment of Oral Medicine and Radiodiagnosis, K. M. Shah Dental College, Sumandeep Vidyapeeth University, Waghodiya, Vadodara, Gujarat, India.

Sangeeta GuptaDepartment of Physiology, All India Institute of Medical Sciences (AIIMS), Gorakhpur, Uttar Pradesh, India.

Gaurav GuptaDepartment of General Surgery, All India Institute of Medical Sciences (AIIMS), Gorakhpur, Uttar Pradesh, India.

Deepika PatidarDepartment of Pedodontics, College of Dental Science and Hospital, Rau, Indore, Madhya Pradesh, India.

Dinesh PatidarDepartment of Trauma and Emergency, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Odisha, India.

Ishita GuptaGovernment Institute of Medical Sciences, Noida, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of serum lipids as tumour markers in the diagnosis of oral cancer and oral potentially malignant disorders (OPMDs) is of interest. Hence, three groups (oral cancer, OPMDs and age and sex matched healthy controls) comprising 40 patients each was selected. Serum lipid profile values (total cholesterol, triglycerides, low density lipoprotein, high density lipoprotein and very low density lipoprotein) were compared among the groups (unpaired t-test and one way-ANOVA) (p-value of <0.05 was considered as significant). Mean values of total serum cholesterol and low density lipoprotein were found to be elevated in cases of oral cancer and oral PMDs as compared to controls with statistical significance (p<0.001). The alterations in levels obtained in the study, support the role of serum lipid profile as biomarkers for oral cancer and OPMDs, yet strengthening of the evidences by long-term follow-up studies with larger sample sizes are warranted to establish the association.

Indexed as

cholesterolhigh density lipoprotein and very low density lipoproteinlipidlow density lipoproteinOral canceroral potentially malignant disorderstriglycerides

Identifiers

PMID41960459

DOI10.6026/973206300220328

PMCPMC13058311

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