ArticleBioinformation2026
Identification of Hub genes in melasma using integrated transcriptomic analysis.
Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Melasma is a prevalent pigmentary disorder or hyper melanosis skin condition. It is characterized by evenly distributed hyperpigmented regions on the light exposed areas of the facial regions. Its management continues to be a therapeutic challenge due to the limited understanding of their pathogenesis. Therefore, it is of interest to report the molecular mechanism of melasma pathogenesis. By using the identification of key genes and pathways via integrate microarray datasets. These transcriptomics studies showed the complex multifactorial molecular mechanisms are involved in melasma production. These key pathways that are involve in oxidative stress, inflammatory signaling and dermal remodeling. This could give insights into a potential therapeutic target such as DNA repair regulators and metabolic stabilizers.
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