Evidence map›Paper›PMID 41960345›Full record

ArticleResearch square2026

Accessing invasion-competent Plasmodium vivax merozoites reveals antibody-dependent NK cell activation.

Jeremy Salvador, Lucas Guselli, Romminea Yeat, Sokchea Lay, Titsophantharoth Thol, Nisa Ya, Lionel Feufack-Donfack, Sievleang Heng, Candice Bohaud, Agnes Orban and 5 more

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jeremy SalvadorInstitut Pasteur du Cambodge.ORCID 0000-0001-7684-4689
Lucas GuselliInstitut Pasteur du Cambodge.
Romminea YeatInstitut Pasteur du Cambodge.
Sokchea LayInstitut Pasteur du Cambodge.
Titsophantharoth TholInstitut Pasteur du Cambodge.
Nisa YaInstitut Pasteur du Cambodge.
Lionel Feufack-DonfackInstitut Pasteur du Cambodge.
Sievleang HengInstitut Pasteur du Cambodge.
Candice BohaudInstitut Pasteur du Cambodge.
Agnes OrbanInstitut Pasteur du Cambodge.
Léa BaldorInstitut Pasteur du Cambodge.
Baura TatInstitut Pasteur du Cambodge.ORCID 0009-0007-6182-4010
Chetan ChitnisInstitut Pasteur.
Tineke CantaertInstitut Pasteur du Cambodge.ORCID 0000-0002-8911-1502
Jean PopoviciInstitut Pasteur du Cambodge.ORCID 0000-0002-3135-1175

Funding

Inter-regional study of transmission, adaptation and pathogenesis of viruses with pandemic potential in Southeast Asia and West/Central AfricaU01AI151758 · NIAID · INSTITUT PASTEUR · PI SAKUNTABHAI, ANAVAJ, SIMON-LORIERE, ETIENNE · 2020 to 2024
$6.7M
Mechanisms of antibody-dependent enhancement of SARS-CoV-2 infectionR01AI137276 · NIAID · ROCKEFELLER UNIVERSITY · PI Stylianos Bournazos · 2018 to 2026
$4.5M
Extent, dynamics and mechanisms of Plasmodium vivax immune evasion caused by PvDBP gene amplificationR01AI173171 · NIAID · INSTITUT PASTEUR DU CAMBODGE · PI Eugenia Lo, Jean POPOVICI · 2023 to 2026
$2.4M
Comprehensive characterization of the genetic factors and the host immune response associated to protection from clinical Plasmodium vivax malariaR01AI175134 · NIAID · INSTITUT PASTEUR DU CAMBODGE · PI TINEKE CANTAERT, Jean POPOVICI · 2023 to 2026
$2.3M
Leveraging access to parasite natural diversity to identify Plasmodium vivax culture-adaptable strain.R61AI187100 · NIAID · INSTITUT PASTEUR DU CAMBODGE · PI Jean POPOVICI · 2025 to 2026
$533k
NIAID NIH HHS R01 AI137276NIAID NIH HHS R01 AI173171NIAID NIH HHS R01 AI175134NIAID NIH HHS R61 AI187100NIAID NIH HHS U01 AI151758Wellcome Trust
6 · The paper itself

Abstract

Malaria pathogenesis and clinical symptoms arise from blood-stage replication of Plasmodium parasites, which depends on rapid invasion of red blood cell by merozoites. Despite the central importance of this stage, direct functional studies of

Identifiers

PMID41960345
PMCPMC13060514

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.