Evidence map›Paper›PMID 41960342›Full record

ArticleResearch square2026

Pre-Transfusion Platelet Counts and Bleeding in Very Low Birth Weight Infants.

Ravi Patel, Elizabeth Stone, Rebecca Birch, Jeanne Hendrickson, Erika Edwards, Ruchika Goel, Eldad Hod, Matthew Karafin, Oliver Karam, Naomi Luban and 7 more

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Ravi PatelEmory University School of Medicine and Children's Healthcare of Atlanta.ORCID 0000-0002-7444-5550
Elizabeth StoneColumbia University.ORCID 0000-0002-4148-7957
Rebecca Birch
Jeanne HendricksonEmory University.ORCID 0000-0002-7928-3132
Erika EdwardsUniversity of Vermont.
Ruchika Goel
Matthew Karafin
Oliver KaramYale.ORCID 0000-0001-6606-1736
Naomi Luban
Jennifer McintoshMedical College of Wisconsin.
Gisela Marrero-Rivera
Marianne Nellis
Jeffrey VanWormer
Nalan YurtseverYale School of Medicine.ORCID 0000-0001-7807-6046
Cassandra JosephsonJohns Hopkins All Children's Hospital.ORCID 0000-0003-2543-991X
Martha Sola-VisnerBoston Children's Hospital and Harvard Medical School.ORCID 0000-0002-0013-598X

Funding

(REDS-IV-P) RECIPIENT EPIDEMIOLOGY AND DONOR EVALUATION STUDY IV-DATA75N92019D00032 · NHLBI · WESTAT, INC. · PI CHAPMAN, KATHY · 2019 to 2025
$19.6M
(REDS-IV-P) RECIPIENT EPIDEMIOLOGY AND DONOR EVALUATION STUDY IV75N92019D00036 · NHLBI · YALE UNIVERSITY · PI HENDRICKSON, JEANNE E · 2019 to 2024
$6.7M
REDS-IV-P DOMESTIC HUBS PHASE 275N92019D00035 · NHLBI · VERSITI WISCONSIN, INC. · PI MAST, ALAN E · 2019 to 2024
$6.6M
REDS-IV-P DOMESTIC HUBS PHASE 275N92019D00037 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HOD, ELDAD ARIE · 2019 to 2024
$6.6M
(REDS-IV-P) RECIPIENT EPIDEMIOLOGY AND DONOR EVALUATION STUDY IV-DOMESTIC HUBS75N92019D00034 · NHLBI · VITALANT · PI CUSTER, BRIAN · 2020 to 2024
$5.3M
1/2 Neonatal Platelet Transfusion Threshold Trial (NeoPlaTT)UH3HL173303 · NHLBI · EMORY UNIVERSITY · PI Ravi Mangal Patel, Martha C. Sola-Visner · 2025 to 2026
$631k
1/2 Neonatal Platelet Transfusion Threshold Trial (NeoPlaTT)UG3HL173303 · NHLBI · EMORY UNIVERSITY · PI PATEL, RAVI MANGAL, SOLA-VISNER, MARTHA C. · 2024 to 2024
$359k
NHLBI NIH HHS 75N92019D00032NHLBI NIH HHS 75N92019D00034NHLBI NIH HHS 75N92019D00035NHLBI NIH HHS 75N92019D00036NHLBI NIH HHS 75N92019D00037NHLBI NIH HHS UG3 HL173303NHLBI NIH HHS UH3 HL173303
6 · The paper itself

Abstract

Objective: Platelet transfusion thresholds for very low birth weight (VLBW, <1500g) infants vary widely, and the role of bleeding on platelet transfusion thresholds is unknown. Study Design: This observational birth cohort study of VLBW infants born in 7 hospitals across the US examined pre-transfusion platelet counts in infants with and without bleeding who received at least 1 platelet transfusion in the first 3 weeks of life using mixed effect linear regression models. Results: Of the 210 transfused infants, most (76%) had bleeding; intraventricular hemorrhage (IVH) was the most common (61%) bleeding type. Pre-transfusion platelet counts were not different among infants with or without bleeding diagnoses (56.3 vs 58.5×10 Conclusion: Infants with or without bleeding diagnoses had similar pre-transfusion platelet counts; infants with severe IVH had higher pre-transfusion platelet counts.

Identifiers

PMID41960342
PMCPMC13060525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.