Evidence map›Paper›PMID 41960089›Full record

ArticleJTCVS open2026

Elevated oxygen extraction during heart transplantation is associated with increased morbidity and mortality: Implications for goal-directed perfusion.

Mark Petrovic, Awab Ahmad, Chen Chia Wang, Aaron M Williams, John Trahanas, Swaroop Bommareddi, Tarek Absi, Eric Quintana, Kevin McGann, Stephen DeVries and 18 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Mark PetrovicDepartment of Cardiac Surgery, Vanderbilt University School of Medicine, Nashville, Tenn.
Awab AhmadDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Chen Chia WangDepartment of Cardiac Surgery, Vanderbilt University School of Medicine, Nashville, Tenn.
Aaron M WilliamsDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
John TrahanasDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Swaroop BommareddiDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Tarek AbsiDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Eric QuintanaDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Kevin McGannDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Stephen DeVriesDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Joshua LowmanDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Aniket S RaliDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Hasan SiddiqiDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Kaushik AmancherlaDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Stacy TsaiDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Marshall BrinkleyDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Jonathan N MenachemDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Dawn PedrottyDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Lynn PunnooseDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
JoAnn LindenfeldDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Suzanne SacksDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Sandip ZalawadiyaDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Anthony LeporeDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Matthew WarhooverDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Matthew BacchettaDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Kelly SchlendorfDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Ashish S ShahDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Brian LimaDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
NCATS NIH HHS UL1 TR000445
6 · The paper itself

Abstract

Background: Goal-directed perfusion (GDP) during cardiopulmonary bypass (CPB) commonly targets indexed oxygen delivery (DO Methods: We retrospectively analyzed adult heart transplantations performed at a single center between November 2021 and June 2025. Minute-level CPB data were extracted. O Results: Among 381 heart transplant recipients, 40 (10.5%) experienced M-M. O Conclusions: During heart transplantation, a higher O

Indexed as

cardiopulmonary bypassgoal directed perfusionheart transplantationoxygen deliveryoxygen extraction ratio

Identifiers

PMID41960089
PMCPMC13059819

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.