Evidence map›Paper›PMID 41960081›Full record

ArticleJTCVS open2026

Improved outcomes with pulsatile paracorporeal ventricular assist device support in children: A single-center experience.

Valerii Iaprintsev, Tyson A Fricke, Edward Buratto, Alexey Zubritskiy, Stephanie Perrier, Lucas Eastaugh, Chris Barnes, Bennett Sheridan, Phillip S Naimo, Christian P Brizard and 2 more

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In one paragraph

Article in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Valerii IaprintsevDepartment of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Australia.
Tyson A FrickeDepartment of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Australia.
Edward BurattoDepartment of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Australia.
Alexey ZubritskiyDepartment of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Australia.
Stephanie PerrierDepartment of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Australia.
Lucas EastaughDepartment of Paediatrics, University of Melbourne, Melbourne, Australia.
Chris BarnesDepartment of Paediatrics, University of Melbourne, Melbourne, Australia.
Bennett SheridanDepartment of Paediatrics, University of Melbourne, Melbourne, Australia.
Phillip S NaimoDepartment of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Australia.
Christian P BrizardDepartment of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Australia.
Jacob MathewDepartment of Paediatrics, University of Melbourne, Melbourne, Australia.
Igor E KonstantinovDepartment of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The Berlin Heart EXCOR (BHE) remains the only long-term mechanical circulatory support option for small children, yet it carries a high risk of morbidity and mortality, most notably from cerebrovascular accidents (CVAs). This study evaluates how the outcomes of children supported with BHE changed with evolving management. Methods: All consecutive patients receiving BHE at our institution from 2009 to 2024 were included. Results: BHE support was used in 75 patients (median age 1 year). Median support duration was 128 days. Transplantation was achieved in 64% (48/75) of patients. BHE was removed because of recovery in 13.3% (10/75), and 21.3% (16/75) died while on BHE support. Overall survival was 87.7%, 80.9%, and 65.9% at 1, 6, and 12 months, respectively. Survival improved significantly after 2019 (hazard ratio, 0.14; 95% confidence interval, 0.03-0.72; Conclusions: Modern BHE management significantly reduces incidence of fatal strokes and improves survival, despite increased duration of support.

Indexed as

Berlin Heartcerebrovascular accidentdilated cardiomyopathymechanical circulatory supportpediatric heart failureventricular assist device

Identifiers

PMID41960081
PMCPMC13059983

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.