Evidence map›Paper›PMID 41960059›Full record

ArticleJTCVS open2026

An early nationwide analysis on the continuous distribution of lung-involved multiorgan transplantation.

Haoran Jiang, Isaac S Alderete, Alexandria L Soto, Matthew Libre, Samantha E Halpern, Oliver K Jawitz, Joshua A Rushakoff, Benjamin R Helmold, Kunal J Patel, Hiroshi Date and 2 more

Abstract read
In one paragraph

Article in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Haoran JiangDepartment of Surgery, Duke University Medical Center, Durham, NC.
Isaac S AldereteDepartment of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pa.
Alexandria L SotoDepartment of Surgery, Duke University Medical Center, Durham, NC.
Matthew LibreDepartment of Surgery, Duke University Medical Center, Durham, NC.
Samantha E HalpernDepartment of Surgery, Massachusetts General Hospital, Boston, Mass.
Oliver K JawitzDepartment of Surgery, Duke University Medical Center, Durham, NC.
Joshua A RushakoffDepartment of Medicine, Duke University Medical Center, Durham, NC.
Benjamin R HelmoldDepartment of Surgery, Duke University Medical Center, Durham, NC.
Kunal J PatelDepartment of Surgery, Duke University Medical Center, Durham, NC.
Hiroshi DateDepartment of Surgery, Duke University Medical Center, Durham, NC.
Jacob KlapperDepartment of Surgery, Duke University Medical Center, Durham, NC.
Matthew G HartwigDepartment of Surgery, Duke University Medical Center, Durham, NC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The impact of continuous distribution on allocation of multiorgan transplantation (MOT) involving lungs remains unexplored. Here we characterize how continuous distribution has affected lung-involved MOT. Methods: We conducted a retrospective study using the United Network for Organ Sharing database. Adults listed for lung-MOT between March 9, 2021, and March 8, 2025, were included. The lung allocation score (LAS) era included the 24 months prior to March 9, 2023, and the composite allocation score (CAS) era comprised 24 months after March 9, 2023. Primary outcomes included transplantation rate, waitlist mortality, and 6-month composite outcome (graft rejection and death) assessed with Kaplan-Meier methods and Poisson regression to estimate transplantation rate and waitlist mortality. Post-transplantation survival was modeled using Cox proportional hazards. Results: Among 498 lung-MOT candidates listed for transplantation during the study period (274 heart-lung, 106 lung-liver, and 101 lung-kidney), 349 underwent transplantation (205 heart-lung, 77 lung-liver, and 60 lung-kidney). The transplantation rate per 100 patient-years increased significantly for all combinations under CAS (heart-lung, 90.5 vs 172.9; lung-liver, 57.9 vs 254.5; lung-kidney, 118.8 vs 194.2; Conclusions: The transition from LAS to CAS enhanced access to transplantation for lung-MOT, while waitlist mortality remained similar. Short-term post-transplant composite outcomes did not differ between eras, supporting the feasibility of CAS for lung-MOT candidates without negatively impacting early outcomes.

Indexed as

CAScontinuous distributionlung transplantmultiorgan transplant

Identifiers

PMID41960059
PMCPMC13059811

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.