Evidence map›Paper›PMID 41960050›Full record

ArticleJTCVS open2026

High-volume centers achieve superior outcomes in left ventricular assist device explant-heart transplantation.

Catherine L B McGeoch, Clayton J Rust, Reshma Kodimerla, Sally El Sammak, Konstantinos S Mylonas, Humza Naqvi, Supreet S Randhawa, Ailin Tang, Michael E Halkos, Muath M Bishawi and 2 more

Abstract read
In one paragraph

Article in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Catherine L B McGeochDivision of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, Ga.
Clayton J RustDivision of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, Ga.
Reshma KodimerlaDivision of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, Ga.
Sally El SammakDivision of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, Ga.
Konstantinos S MylonasDivision of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, Ga.
Humza NaqviDivision of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, Ga.
Supreet S RandhawaDivision of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, Ga.
Ailin TangDivision of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, Ga.
Michael E HalkosDivision of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, Ga.
Muath M BishawiDivision of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, Ga.
Mani A DaneshmandDivision of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, Ga.
Joshua L ChanDivision of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, Ga.

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Institutional Career Development CoreKL2TR002381 · NCATS · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Anandi Nayan Sheth · 2017 to 2026
$14.1M
NCATS NIH HHS KL2 TR002381NCATS NIH HHS UL1 TR002378
6 · The paper itself

Abstract

Background: Left ventricular assist device Methods: Adult patients who underwent LVAD explantation with OHT between 2011 and 2024 were identified in the Organ Procurement and Transportation Network/United Network for Organ Sharing registry. Using a rank-order method based on surgical volume, centers were stratified as either high volume or low volume. The primary outcome was 1-year survival; secondary outcomes included graft failure, ischemic time, dialysis, stroke, and hospital length of stay. Kaplan-Meier and Cox regression analyses were performed to assess survival and predictors of mortality. Results: A total of 2863 patients across 121 centers were analyzed. Eight high-volume centers performed 31.3% (897 cases) of all LVAD explant-OHTs. Baseline characteristics, including heart failure etiology and LVAD device type, were similar in the 2 groups. High-volume centers demonstrated decreased ischemic time (mean, 3.1 ± 1.3 hours vs 3.5 ± 1.4 hours; Conclusions: High-volume centers were associated with superior survival and improved perioperative outcomes following LVAD explant-OHT.

Indexed as

allograft survivalcenters of excellenceclinical outcomesheart transplantleft ventricular assist devicessurgical case volume

Identifiers

PMID41960050
PMCPMC13059826

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.