ArticleFrontiers in pediatrics2026
Efficacy of endoscopic retrograde appendicitis therapy in children with suppurative vs. simple appendicitis: a retrospective cohort study.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To evaluate the efficacy of endoscopic retrograde appendicitis therapy (ERAT) in the treatment of pediatric suppurative appendicitis. Methods: In this retrospective cohort study, children undergoing ERAT for acute appendicitis between January 2019 to March 2025 were categorized according to disease severity into suppurative or simple appendicitis groups. Data encompassing baseline characteristics, preoperative profiles, procedural outcomes, and follow-up were collected and subjected to intergroup comparison. Results: The study included 61 children (31 suppurative, 30 simple). Two patients in the suppurative group were excluded from the follow-up analysis due to missing data at the one-week time point. Preoperative fever, vomiting, appendicoliths, and inflammatory markers were significantly more common in the suppurative group (all Conclusion: For suppurative appendicitis, particularly with a thin-walled appendix or large fecalith, ERAT is not recommended due to low success rates and perforation risk; laparoscopic appendectomy remains the standard. ERAT is a safe, effective organ-preserving option only for carefully selected patients with simple appendicitis or select non-necrotizing fecalith impaction.
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