ArticleCureus2026
Simple Can Be Effective: A Brief Naloxone Training in Preclinical Medical Education.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Opioid overdose remains a leading cause of preventable mortality in the United States. Early education on overdose recognition and naloxone administration is recommended in medical training, yet its implementation in preclinical curricula is often limited by time and resource constraints. This study evaluated the efficacy of a brief, didactic naloxone training integrated into a mandatory preclinical wellness session in improving first-year medical students' confidence in opioid knowledge, overdose recognition, and naloxone administration. Methods The first-year medical students at a single U.S. medical school were invited to complete anonymous pre- and post-training surveys surrounding a 12-minute naloxone training video. Survey items used a five-point Likert scale assessing confidence in opioid knowledge, overdose recognition, appropriate response actions, and understanding of naloxone. Pre- and post-survey responses were analyzed as independent samples using two-tailed Mann-Whitney U tests. Effect sizes were calculated using rank-biserial correlation. Results A total of 151 pre-survey and 133 post-survey responses were analyzed. Post-training responses demonstrated significantly higher confidence across all survey questions, including defining opioids, recognizing opioid overdose, knowing appropriate actions to take, and understanding naloxone (all p<0.001). Large effect sizes were observed for these outcomes (rank-biserial correlation range: 0.65-0.77). Participants also reported high confidence in their ability to administer intranasal naloxone following the intervention (median (IQR): 5 (4-5)). Conclusions A brief, resource-efficient naloxone training significantly improved preclinical medical students' self-reported confidence in opioid overdose recognition and naloxone administration. This intervention demonstrates a scalable approach for integrating harm-reduction education into preclinical medical curricula and beyond.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.