Evidence map›Paper›PMID 41959988›Full record

ArticleCureus2026

A Persistent Pneumonia or an Uncommon Condition: A Case of Immunotherapy-Induced Pneumonitis.

Jessica Fidalgo, Carina Santos, Inês Sequeira, Catarina Valente, Patrícia Tenreiro

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jessica FidalgoDepartment of Internal Medicine, Guarda Local Health Unit, Guarda, PRT.
Carina SantosDepartment of Internal Medicine, Guarda Local Health Unit, Guarda, PRT.
Inês SequeiraDepartment of Oncology, Guarda Local Health Unit, Guarda, PRT.
Catarina ValenteDepartment of Internal Medicine, Guarda Local Health Unit, Guarda, PRT.
Patrícia TenreiroDepartment of Internal Medicine, Guarda Local Health Unit, Guarda, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy with immune checkpoint inhibitors has revolutionized the treatment of metastatic renal cell carcinoma. However, it may be associated with severe toxicity, particularly immune-mediated pneumonitis. The present case report describes a 60-year-old patient diagnosed with stage IV clear cell renal carcinoma undergoing treatment with nivolumab, who developed severe partial respiratory failure refractory to empirical antibiotic therapy. After exclusion of other causes, namely, cardiovascular and infectious etiologies, immune-mediated pneumonitis was suspected, and systemic corticosteroid therapy was initiated, resulting in significant clinical and radiological improvement. This case illustrates immune-mediated pneumonitis in the context of nivolumab treatment, highlighting the importance of an accurate differential diagnosis in patients receiving immunotherapy and the early initiation of corticosteroid therapy when immune-related pneumonitis is suspected.

Indexed as

corticosteroid therapyimmune-mediated pneumonitisimmunotherapymetastatic renal cell carcinomanivolumab

Identifiers

PMID41959988
PMCPMC13058637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.