Evidence map›Paper›PMID 41959857›Full record

ArticleJournal of applied crystallography2026

Viljar J Femoen, Laura Pacoste, Michał Leszek Chodkiewicz, Pavel V Afonine, Billy K Poon, Marta Kulik, Łukasz Golon, Nigel W Moriarty, Paul D Adams, Gerhard Hofer and 3 more

Abstract read
In one paragraph

Article in Journal of applied crystallography, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Towards routine accurate electron-density studies of biological macromolecules.Acta crystallographica. Section D, Structural biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Viljar J FemoenDepartment of Chemistry University of Stockholm Stockholm Sweden.
Laura PacosteDepartment of Chemistry University of Stockholm Stockholm Sweden.ORCID https://orcid.org/0009-0005-6090-8736
Michał Leszek ChodkiewiczBiological and Chemical Research Center, Faculty of Chemistry University of Warsaw Warsaw Poland.ORCID https://orcid.org/0000-0003-4448-445X
Pavel V AfonineMolecular Biophysics and Integrated Bioimaging Division Lawrence Berkeley National Laboratory Berkeley CA USA.
Billy K PoonMolecular Biophysics and Integrated Bioimaging Division Lawrence Berkeley National Laboratory Berkeley CA USA.
Marta KulikBiological and Chemical Research Center, Faculty of Chemistry University of Warsaw Warsaw Poland.
Łukasz GolonBiological and Chemical Research Center, Faculty of Chemistry University of Warsaw Warsaw Poland.
Nigel W MoriartyMolecular Biophysics and Integrated Bioimaging Division Lawrence Berkeley National Laboratory Berkeley CA USA.ORCID https://orcid.org/0000-0001-8857-9464
Paul D AdamsMolecular Biophysics and Integrated Bioimaging Division Lawrence Berkeley National Laboratory Berkeley CA USA.
Gerhard HoferDepartment of Chemistry University of Stockholm Stockholm Sweden.
Paulina Maria DominiakBiological and Chemical Research Center, Faculty of Chemistry University of Warsaw Warsaw Poland.ORCID https://orcid.org/0000-0002-1466-1243
Dorothee LiebschnerMolecular Biophysics and Integrated Bioimaging Division Lawrence Berkeley National Laboratory Berkeley CA USA.ORCID https://orcid.org/0000-0003-3921-3209
Xiaodong ZouDepartment of Chemistry University of Stockholm Stockholm Sweden.ORCID https://orcid.org/0000-0001-6748-6656

Funding

Phenix: providing high quality software to the research community for crystallography and cryo-EMR24GM141254 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PAUL David ADAMS · 2021 to 2026
$9.2M
NIGMS NIH HHS R24 GM141254
6 · The paper itself

Abstract

Multipolar scattering models, such as the transferable aspherical atom model, account for atomic chemical interactions and provide a more accurate representation of experimental data. However, the simpler independent atom model (IAM), which assumes non-interacting atoms, is the only model available in the most widely used macromolecular refinement programs. This is primarily because IAM offers a hard-to-beat combination of computational efficiency and modelling power at typical macromolecular resolutions. By contrast, more accurate multipolar modelling has historically been limited due to its computational cost and the absence of an interface between software capable of calculating structure factors and gradients based on multipolar models and software designed for macromolecular refinement. This work introduces

Indexed as

cctbxcryoEMmacromolecular refinementMATTS data bankPhenixquantum crystallographytransferable aspherical atom model

Identifiers

PMID41959857
PMCPMC13060618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.