Evidence map›Paper›PMID 41959749›Full record

ArticleFrontiers in neuroscience2026

Evaluating post-concussion symptom profiles using the convergence insufficiency symptom survey in a pediatric and adolescent cohort.

Debora Ghosh, Sophia Marusic, Jennifer X Haensel, Carissa H Wu, Kristin E Slinger, Neerali Vyas, Christabel A Ameyaw Baah, Amber Hu, Joellen Leonen, Caitlyn Y Lew and 7 more

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Article in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Debora GhoshBoston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Sophia MarusicBoston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Jennifer X HaenselSpencer Center for Vision Research, Byers Eye Institute at Stanford University, Palo Alto, CA, United States.
Carissa H WuBoston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Kristin E SlingerSpencer Center for Vision Research, Byers Eye Institute at Stanford University, Palo Alto, CA, United States.
Neerali VyasBoston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Christabel A Ameyaw BaahSpencer Center for Vision Research, Byers Eye Institute at Stanford University, Palo Alto, CA, United States.
Amber HuSpencer Center for Vision Research, Byers Eye Institute at Stanford University, Palo Alto, CA, United States.
Joellen LeonenSpencer Center for Vision Research, Byers Eye Institute at Stanford University, Palo Alto, CA, United States.
Caitlyn Y LewSpencer Center for Vision Research, Byers Eye Institute at Stanford University, Palo Alto, CA, United States.
Gayathri SrinivasanSpencer Center for Vision Research, Byers Eye Institute at Stanford University, Palo Alto, CA, United States.
Amir NorouzpourSpencer Center for Vision Research, Byers Eye Institute at Stanford University, Palo Alto, CA, United States.
Erin JeneweinPennsylvania College of Optometry at Salus University, Philadelphia, PA, United States.
Siva MeiyeppenPennsylvania College of Optometry at Salus University, Philadelphia, PA, United States.
Mitchell ScheimanPennsylvania College of Optometry at Salus University, Philadelphia, PA, United States.
Tawna L Roberts *Spencer Center for Vision Research, Byers Eye Institute at Stanford University, Palo Alto, CA, United States.
Aparna Raghuram *Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This multicenter study aimed to compare symptoms in pediatric and adolescent patients with and without concussion using the Convergence Insufficiency Symptom Survey (CISS). We further examined symptom profiles of concussed patients with and without vergence and/or accommodation deficits. Methods: Children aged 8 to <18 years, diagnosed with concussion 4 weeks to 12 months prior and visually normal controls underwent comprehensive testing of vergence and accommodation. Participants completed the 15-item CISS, with somatic (CISS-S), performance (CISS-P), and vision (CISS-V) subscores. Mann-Whitney U tests compared total CISS scores and normalized subscores between concussed and control groups, and concussed participants with and without vergence and/or accommodative deficits. Results: Among 66 eligible participants (34 concussed, median age 15.0 [interquartile range, IQR: 12.2-16.0]; 32 controls, median age 13.0 [11.0-14.0]), concussed individuals had substantially higher total CISS scores (median 26.0 [19.25-36.75] vs. 4.0 [1.0-7.0]; Conclusion: Vergence and accommodation deficits were associated with higher CISS vision and performance related subscores. Elevated symptom reporting in the somatic and performance subscores in concussed may indicate strain in the vergence and accommodative system, as evidenced by the increased subjective discomfort and difficulty during tasks like reading and near work. Concurrent assessment of vergence and accommodation alongside CISS symptom subscores may identify patients for vision rehabilitation, aimed at improving vergence and accommodation function and reducing somatic and performance-related symptoms.

Indexed as

accommodationadolescentconcussionpediatricvergencevision symptoms

Identifiers

PMID41959749
PMCPMC13056603

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.