ArticleThe South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa2026
Clinical and socio-demographic characteristics associated with perinatal depression and human immunodeficiency virus.
Article in The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Perinatal depression is highly prevalent in South Africa. Human immunodeficiency virus (HIV), a known risk factor for depression, affects a large proportion of South African women of reproductive age. Few studies have compared depressive symptoms and associated risk factors in HIV-positive and HIV-negative pregnant and postpartum women, despite both conditions being linked to adverse maternal and child outcomes. Aim: To compare socio-demographic and clinical characteristics of HIV-positive and HIV-negative women in the perinatal period attending a maternal mental health clinic. Setting: The maternal mental health clinic at Chris Hani Baragwanath Academic Hospital in Soweto, Johannesburg. Methods: A retrospective record review was conducted on 190 patients (HIV-positive: Results: The prevalence of significant depressive symptoms (Edinburgh Postnatal Depression Scale [EPDS] score > 13) was 43.2% ( Conclusion: Perinatal depressive symptoms were highly prevalent. Human immunodeficiency virus-positive women were more likely to report poor social support, a key risk factor for depressive symptoms. The findings of this study underscore the need for targeted psychosocial interventions. Contribution: This study encourages further research to explore risk factors associated with perinatal depression, especially in HIV-positive women.
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