Evidence map›Paper›PMID 41959600›Full record

ArticleACG case reports journal2026

Crohn's Disease Complicated by Undiagnosed Hemophilia A: A Case of Recurrent Massive Lower Gastrointestinal Bleeding.

Caroline Soares, Miguel Rodrigues, Diana Martins, Paula Sousa, Eugénia Cancela, Maria João Ferreira, Carlos Casimiro, Américo Silva, Paula Ministro

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Caroline SoaresDepartment of Gastroenterology, Viseu Dão-Lafões Health Unit, Viseu, Portugal.ORCID https://orcid.org/0009-0005-2994-9054
Miguel RodriguesDepartment of General Surgery, Viseu Dão-Lafões Health Unit, Viseu, Portugal.
Diana MartinsDepartment of Gastroenterology, Viseu Dão-Lafões Health Unit, Viseu, Portugal.
Paula SousaDepartment of Gastroenterology, Viseu Dão-Lafões Health Unit, Viseu, Portugal.
Eugénia CancelaDepartment of Gastroenterology, Viseu Dão-Lafões Health Unit, Viseu, Portugal.
Maria João FerreiraDepartment of General Surgery, Viseu Dão-Lafões Health Unit, Viseu, Portugal.
Carlos CasimiroDepartment of General Surgery, Viseu Dão-Lafões Health Unit, Viseu, Portugal.
Américo SilvaDepartment of Gastroenterology, Viseu Dão-Lafões Health Unit, Viseu, Portugal.
Paula MinistroDepartment of Gastroenterology, Viseu Dão-Lafões Health Unit, Viseu, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe gastrointestinal bleeding is a rare but potentially fatal complication of Crohn's disease (CD). In the literature, there are some previously described cases, but there are no clear guidelines on how to manage these patients. We present the case of a patient with ileal CD and previously unknown hemophilia A. The patient experienced 2 episodes of massive intestinal bleeding, the last one requiring surgery. The disease proved difficult to treat with extension to upper gastrointestinal tract, despite being on biological therapy. In addition, diagnosis of coagulation disorders as hemophilia in patients with CD is rare but potentially catastrophic, requiring prepared multidisciplinary teams.

Indexed as

Crohn's diseasehemophilia A

Identifiers

PMID41959600
PMCPMC13061523

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.