ArticlebioRxiv : the preprint server for biology2026
Flexible integration of corollary discharge and sensory feedback signals in somatosensory cortex.
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Motor control depends on the continuous integration of motor and sensory signals to maintain accurate estimates of body state, yet neural evidence for this integration remains elusive. Here, we investigated the interaction of motor corollary discharge and proprioceptive feedback signals in area 2 of monkey somatosensory cortex during voluntary and externally-perturbed reaching tasks. Though single neurons had mixed responses to corollary discharge and sensory feedback, we disentangled these signals at the population level to discover they occupy approximately orthogonal subspaces. Integrating information across these subspaces enabled accurate body state estimation prior to feedback arrival during voluntary movements. Moreover, the orthogonal population geometry of corollary discharge and sensory feedback enabled cancellation of movement-related signals to improve the decoding of external perturbations. Together, these results identified orthogonality as a population-level coding strategy for flexible integration of motor and sensory signals to support multiple distinct computations.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.