Evidence map›Paper›PMID 41959487›Full record

ArticlebioRxiv : the preprint server for biology2026

Evolutionary rewiring of the endomesoderm gene regulatory networks specify skeleton secreting cells in stony corals.

Ryan M Besemer, Laura Slama, Nicole Fogarty, Sarah Arnold, Koty Sharp, Leslie S Babonis, Jacob F Warner

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ryan M BesemerBiology and Marine Biology, UNC-Wilmington, Wilmington NC.
Laura SlamaBiology and Marine Biology, UNC-Wilmington, Wilmington NC.
Nicole FogartyBiology and Marine Biology, UNC-Wilmington, Wilmington NC.
Sarah ArnoldDepartment of Ecology and Evolutionary Biology, Cornell University, Ithaca NY.
Koty SharpDepartment of Biology, Marine Biology, and Environmental Science, Roger Williams University, Bristol RI.
Leslie S BabonisDepartment of Ecology and Evolutionary Biology, Cornell University, Ithaca NY.
Jacob F WarnerBiology and Marine Biology, UNC-Wilmington, Wilmington NC.

Funding

Training CoreP20GM103430 · NIGMS · UNIVERSITY OF RHODE ISLAND · PI Christopher Lee Hemme · 2012 to 2026
$63.6M
Gene Regulation and the Origin of New Cell TypesR35GM147253 · NIGMS · CORNELL UNIVERSITY · PI Leslie S Babonis · 2022 to 2026
$2.0M
CONSTRUCTING A HIGH-RESOLUTION GENE REGULATORY NETWORK OF EMTR15GM139113 · NIGMS · UNIVERSITY OF NORTH CAROLINA WILMINGTON · PI WARNER, JACOB F · 2021 to 2021
$416k
NIGMS NIH HHS P20 GM103430NIGMS NIH HHS R15 GM139113NIGMS NIH HHS R35 GM147253
6 · The paper itself

Abstract

Stony corals are the only cnidarians to secrete a robust calcium carbonate skeleton making them the critical keystone species for one of the most diverse marine ecosystems on earth: coral reefs. Despite their importance, very little is known about the genetic interactions that drive the earliest life history stages of corals during which coral-specific traits emerge, such as specification of coral skeletogenic cells. Here, we used a combination of chromatin profiling and gene expression assays to derive the

Indexed as

CnidarianCoralDevelopmentGene regulatory network

Identifiers

PMID41959487
PMCPMC13060117

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.