Evidence map›Paper›PMID 41959475›Full record

ArticlebioRxiv : the preprint server for biology2026

Aditi Singh, Saman Abbaspoor, Leeyup Chung, Maxwell J Heinrich, Scellig Stone, Hart Lidov, Beatriz Maio, Tien Phuoc-Tran, Jaeyoung Yoon, Jiawen Teng and 8 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Aditi SinghHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.
Saman AbbaspoorHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.
Leeyup ChungHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.
Maxwell J HeinrichHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.
Scellig StoneDepartment of Neurosurgery, Harvard Medical School, Boston, MA, USA.
Hart LidovDepartment of Pathology, Harvard Medical School, Boston, MA, USA.
Beatriz MaioHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.
Tien Phuoc-TranHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.
Jaeyoung YoonHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-4354-4169
Jiawen TengHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.
Catalina Martinez-ReyesHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.
Elijah HammarlundHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.
Xiguang XuHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.
Alexander RotenbergHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.
Jeff GavornikHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.
Brielle FergusonHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.
Jordan S FarrellHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.
Emily K OsterweilHansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.

Funding

Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI Hisashi Umemori · 2021 to 2026
$9.4M
Supplement request for Training GrantT32NS007473 · NINDS · CHILDREN'S HOSPITAL BOSTON · PI Elizabeth C. Engle, Thomas L. Schwarz · 1999 to 2026
$6.9M
Dissecting Hypothalamic Pathways for Seizure ControlR00NS126725 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI Jordan Stewart Farrell · 2024 to 2026
$740k
Dissecting hypothalamic pathways for seizure controlK99NS126725 · NINDS · STANFORD UNIVERSITY · PI FARRELL, JORDAN STEWART · 2022 to 2023
$229k
NICHD NIH HHS P50 HD105351NINDS NIH HHS K99 NS126725NINDS NIH HHS R00 NS126725NINDS NIH HHS T32 NS007473Wellcome Trust
6 · The paper itself

Abstract

Transcriptional silencing of

Identifiers

PMID41959475
PMCPMC13060901

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.