Evidence map›Paper›PMID 41959463›Full record

ArticlebioRxiv : the preprint server for biology2026

A widespread gut bacterial lineage distinguished by redox metabolism and phage defense.

Cecilia Noecker, Lu Guo, Cyrille Daté, Nitee Rai, Fadima Daramy, Luis A Ramirez Hernandez, Than S Kyaw, Kai R Trepka, Chhedi Lal Gupta, Connie W Y Ha and 3 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cecilia NoeckerDepartment of Biological Sciences, Minnesota State University Mankato, Mankato, MN.ORCID 0000-0003-1417-2383
Lu GuoDepartment of Biological Sciences, Minnesota State University Mankato, Mankato, MN.
Cyrille DatéDepartment of Biological Sciences, Minnesota State University Mankato, Mankato, MN.
Nitee RaiDepartment of Biological Sciences, Minnesota State University Mankato, Mankato, MN.
Fadima DaramyDepartment of Biological Sciences, Minnesota State University Mankato, Mankato, MN.
Luis A Ramirez HernandezDepartment of Biological Sciences, Minnesota State University Mankato, Mankato, MN.
Than S KyawDepartment of Biological Sciences, Minnesota State University Mankato, Mankato, MN.
Kai R TrepkaDepartment of Biological Sciences, Minnesota State University Mankato, Mankato, MN.
Chhedi Lal GuptaBenioff Center for Microbiome Medicine, University of California San Francisco, San Francisco, CA.
Connie W Y HaBenioff Center for Microbiome Medicine, University of California San Francisco, San Francisco, CA.
Joel BabdorDepartment of Biological Sciences, Minnesota State University Mankato, Mankato, MN.
Matthew H SpitzerDepartment of Biological Sciences, Minnesota State University Mankato, Mankato, MN.
Peter J TurnbaughDepartment of Biological Sciences, Minnesota State University Mankato, Mankato, MN.ORCID 0000-0002-0888-2875

Funding

Predicting and preventing drug metabolism by the human gut microbiomeR01HL122593 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Peter James Turnbaugh · 2016 to 2026
$5.7M
Immune determinants of progression from Oral Epithelial Dysplasia to Oral Squamous Cell Carcinoma by precision multiplexed imagingR01DE032033 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Matthew Spitzer · 2022 to 2026
$3.8M
Metabolism of cancer chemotherapeutics by the human gut microbiomeR01CA255116 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Peter James Turnbaugh · 2023 to 2026
$3.1M
Host-microbiome interactions shape the metabolic effects of ketogenic dietsR01DK114034 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TURNBAUGH, PETER JAMES · 2020 to 2024
$2.5M
Early identification of immunotherapy resistance through integrated multiparameter imagingR01CA290027 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Mekhail Anwar, Matthew Spitzer · 2025 to 2026
$1.4M
Systems-level analysis of the metabolism and ecology of genetically intractable gut bacteriaF32GM140808 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NOECKER, CECILIA · 2021 to 2022
$134k
NCI NIH HHS R01 CA255116NCI NIH HHS R01 CA290027NHLBI NIH HHS R01 HL122593NIDCR NIH HHS R01 DE032033NIDDK NIH HHS R01 DK114034NIGMS NIH HHS F32 GM140808
6 · The paper itself

Abstract

Genomic variation within gut microbial species can have consequences for host health and disease. However, for low abundance species, these variations can be difficult to capture by both culture-dependent and -independent approaches. Here, we focus on the prevalent but low abundance gut Actinomycetota

Identifiers

PMID41959463
PMCPMC13060105

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.