Evidence map›Paper›PMID 41959388›Full record

ArticlebioRxiv : the preprint server for biology2026

STI1 domains coordinate partitioning of UBQLN2 into stress-induced condensates.

William Haws, Thuy P Dao, Bridget Varner, Holly B Jones, Mallory P Brown, Carlos A Castañeda

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

William HawsDepartment of Chemistry, Syracuse University, Syracuse NY.
Thuy P DaoDepartment of Chemistry, Syracuse University, Syracuse NY.ORCID 0000-0002-2168-7679
Bridget VarnerDepartment of Biology, Syracuse University, Syracuse NY.ORCID 0009-0002-4998-5421
Holly B JonesDepartment of Biology, Syracuse University, Syracuse NY.
Mallory P BrownProgram in Neuroscience, Syracuse University, Syracuse NY.ORCID 0009-0000-4143-3804
Carlos A CastañedaDepartment of Chemistry, Syracuse University, Syracuse NY.ORCID 0000-0001-9634-0867

Funding

The Biophysics Collaborative Access Team (User Training and Outreach)P30GM138395 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI THOMAS C IRVING · 2021 to 2026
$16.5M
The Role and Mechanisms of UBQLN2-mediated Phase Transitions in the Assembly and Disassembly of Biomolecular CondensatesR01GM136946 · NIGMS · SYRACUSE UNIVERSITY · PI CASTANEDA, CARLOS ANTONIO · 2020 to 2024
$1.5M
Architecture and function of condensates formed by ubiquitin-binding shuttle proteins and protein quality control componentsR35GM158070 · NIGMS · SYRACUSE UNIVERSITY · PI Carlos Antonio Castaneda · 2025 to 2026
$879k
NIGMS NIH HHS P30 GM138395NIGMS NIH HHS R01 GM136946NIGMS NIH HHS R35 GM158070
6 · The paper itself

Abstract

UBQLN2 is a ubiquitin-binding shuttle protein that undergoes phase separation

Indexed as

condensate formationdomain mappingheat stresslive-cell imagingphase separationSTI1UBQLN2

Identifiers

PMID41959388
PMCPMC13060323

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.