Evidence map›Paper›PMID 41959321›Full record

ArticlebioRxiv : the preprint server for biology2026

Neural cell state modulation by

Yongxing Gong, Armin Bayati, Tyler J Alban, Prerana Parthasarathy, Fang Zhou, Vladimir Makarov, Yuhang Zhao, Chienwen Su, Jackson G Schumacher, Vijay Singh and 8 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Yongxing GongDept. of Cancer Sciences and Global Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, USA.
Armin BayatiAligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD, USA.ORCID 0000-0002-5960-0479
Tyler J AlbanDept. of Cancer Sciences and Global Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, USA.
Prerana ParthasarathyDept. of Cancer Sciences and Global Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, USA.
Fang ZhouAligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD, USA.
Vladimir MakarovDept. of Cancer Sciences and Global Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, USA.
Yuhang ZhaoAligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD, USA.
Chienwen SuAligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD, USA.
Jackson G SchumacherAligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD, USA.ORCID 0009-0000-4227-4710
Vijay SinghAligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD, USA.
Laura A Volpicelli-DaleyAligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD, USA.ORCID 0000-0001-8934-4018
Wen LuoThe Neuro's Early Drug Discovery Unit, McGill University, Montreal, QC, Canada.
Thomas M DurcanThe Neuro's Early Drug Discovery Unit, McGill University, Montreal, QC, Canada.
Shovan DuttaDept. of Cancer Sciences and Global Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, USA.
Michael A SchwarzschildAligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD, USA.ORCID 0000-0001-6019-8280
Jennifer A JohnstonNysnoBio, Mill Valley, CA, USA.
Timothy A ChanDept. of Cancer Sciences and Global Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, USA.ORCID 0000-0002-9265-0283
Xiqun ChenAligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD, USA.ORCID 0000-0001-8582-8891

Funding

MC1R Basis of Melanoma-Parkinson's Link and Neuroprotective Potential of MC1RR01NS102735 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CHEN, XIQUN · 2018 to 2022
$1.8M
NINDS NIH HHS R01 NS102735
6 · The paper itself

Abstract

Parkin, an E3 ubiquitin ligase encoded by

Identifiers

PMID41959321
PMCPMC13060259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.