ArticlebioRxiv : the preprint server for biology2026
Functional Analysis of Late-Onset Alzheimer's Disease Risk Genes in
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Genome-wide studies in late-onset Alzheimer's disease (LOAD) have uncovered many risk loci, yet identifying the causal genes and clarifying how these genetic signals connect to molecular and cellular mechanisms relevant to AD pathogenesis Methods: Using Results: Lifespan was unaffected by most knockdowns, and only Conclusions: Our findings show that conserved homologs of several understudied LOAD risk genes causally modulate neuronal aging
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