Evidence map›Paper›PMID 41959088›Full record

ArticlebioRxiv : the preprint server for biology2026

Monitoring Autonomic Tone During Spinal Cord Neuromodulation Using Wearable AURIS Sensor.

Ryan S Bohluli, Angelica F Lopez, Pierce L Perkins, Kenzi M Griffith, Avaneesh Babu, Sung-Min Cho, Nitish V Thakor

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ryan S BohluliDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA.ORCID 0000-0003-4182-5773
Angelica F LopezDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA.ORCID 0000-0002-4163-2915
Pierce L PerkinsDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA.ORCID 0000-0003-1564-4258
Kenzi M GriffithDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA.ORCID 0009-0004-4468-1255
Avaneesh BabuDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA.ORCID 0009-0003-2904-8091
Sung-Min ChoDepartment of Neurology, Johns Hopkins Hospital, Baltimore, Maryland 21205, USA.ORCID 0000-0002-5132-0958
Nitish V ThakorDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA.ORCID 0000-0002-9981-9395

Funding

Consequences of Cardiac Arrest: Brain InjuryR01HL071568 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI GEOCADIN, ROMERGRYKO, THAKOR, NITISH VYOMESH · 2003 to 2022
$8.4M
Translational Technologies for Ameliorating Brain InjuryR01HL139158 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI KANNAN, SUJATHA, THAKOR, NITISH VYOMESH · 2018 to 2021
$2.1M
NHLBI NIH HHS R01 HL071568NHLBI NIH HHS R01 HL139158
6 · The paper itself

Abstract

The transition of bioelectronic medicine to clinical use is currently limited by a lack of non-invasive sensors capable of measuring autonomic tone during active neuromodulation. Conventional monitoring modalities, such as mean arterial pressure (MAP) and Ag/AgCl chest electrodes, are often invasive, cumbersome, or susceptible to motion artifacts. Here, we present a novel framework employing an in-ear sensor (AURIS) to continuously monitor heart rate variability (HRV) during therapeutic neuromodulation. These sensors utilize a polydimethylsiloxane (PDMS) substrate to ensure biocompatibility and superior conformability. Experiments in a rodent model (

Indexed as

In-ear sensorPEDOT:PSSWearable sensors

Identifiers

PMID41959088
PMCPMC13061052

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.