Evidence map›Paper›PMID 41959033›Full record

ArticlebioRxiv : the preprint server for biology2026

Population-level genome sequencing reveals distinct Mycobacterium tuberculosis intrahost mutational trajectories in simian immunodeficiency virus co-infected and antiretroviral treated non-human primates.

Michael C Chao, Michael R Chase, Shoko Wakabayashi, Andrew Vickers, Byron Roman, Forrest Hopkins, Peter H Culviner, Maximilian G Marin, Pauline Maiello, Collin R Dietrich and 4 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Michael C ChaoDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.ORCID 0000-0003-3158-7337
Michael R ChaseDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.
Shoko WakabayashiDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.
Andrew VickersDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.
Byron RomanDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.
Forrest HopkinsDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.
Peter H CulvinerDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.ORCID 0000-0003-0605-5849
Maximilian G MarinDepartment of Data Science, Dana-Farber Cancer Institute, Boston, USA.
Pauline MaielloDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States.
Collin R DietrichCenter for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.ORCID 0000-0002-7635-9699
Zandrea AmbroseDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States.ORCID 0000-0002-8610-2766
Philana Ling LinCenter for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.ORCID 0000-0001-5169-3714
Qingyun LiuDepartment of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States.
Sarah M FortuneDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.ORCID 0000-0001-7565-9975

Funding

IMMUNE MECHANISMS OF PROTECTION AGAINST MYCOBACTERIUM TUBERCULOSIS CENTER (IMPAC-TB)75N93019C00071 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI FORTUNE, SARAH · 2019 to 2025
$57.3M
Influence of SIV replication on TB progression and immunityR01AI134195 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AMBROSE, ZANDREA, LIN, PHILANA LING · 2017 to 2021
$4.8M
NIAID NIH HHS R01 AI134195NIH HHS 75N93019C00071
6 · The paper itself

Abstract

Whole genome sequencing of

Identifiers

PMID41959033
PMCPMC13060361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.