ArticleJournal of Indian Association of Pediatric Surgeons
Long-term Outcomes of Bladder Exstrophy-Epispadias Complex: A Multicenter Study by Indian Association of Pediatric Surgeons.
Article in Journal of Indian Association of Pediatric Surgeons. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Bladder exstrophy-epispadias complex (BEEC) requires complex reconstruction, yet long-term comparative outcomes from low- and middle-income countries are limited. Materials and Methods: This Indian Association of Pediatric Surgeons (IAPS) multicenter, retrospective cohort study included 59 patients (2000-2020) stratified into modern staged repair of exstrophy (MSRE, Results: The mean continence score was 3.47 ± 0.97 (95% confidence interval [CI]: 3.22-3.73). CPRE (4.15 ± 1.11) and RSTM (4.0 ± 1.29) significantly outperformed MSRE (3.02 ± 0.97) (Bonferroni: Conclusion: CPRE demonstrated the most favorable long-term outcomes, with significantly better continence, higher bladder capacities, fewer reoperations, and superior quality of life compared with MSRE. RSTM yielded encouraging results but requires larger cohorts. This IAPS study identifies early surgery and bladder neck reconstruction as key predictors of success, while underscoring the urgent need for standardized, prospective surveillance of renal, sexual, and reproductive health in BEEC patients and need for longer follow-up.
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