Evidence map›Paper›PMID 41958674›Full record

ArticleFrontiers in immunology2026

TCR repertoire shaping of naïve T cell subsets in human ontogeny.

Mikhail Yu Myshkin, Sofya A Leyn, Evgeny S Egorov, Pavel V Shelyakin, Dmitry B Staroverov, Irina A Shagina, Natalia E Kan, Kseniia R Lupyr, Ekaterina V Barsova, Elena V Dzyubinskaya and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. T Cell Thoughts.Immunological reviews · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Mikhail Yu MyshkinShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.
Sofya A LeynShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.
Evgeny S EgorovShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.
Pavel V ShelyakinAbu Dhabi Stem Cells Center, Abu Dhabi, United Arab Emirates.
Dmitry B StaroverovShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.
Irina A ShaginaShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.
Natalia E KanFederal State Budget Institution (FSBI) «National Medical Research Center for Obstetrics, Gynecology and Perinatology Named After Academician V. I. Kulakov» Ministry of Health of the Russian Federation, Moscow, Russia.
Kseniia R LupyrShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.
Ekaterina V BarsovaShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.
Elena V DzyubinskayaDepartment of Immunology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
Yendry Ventura-CarmenateAbu Dhabi Stem Cells Center, Abu Dhabi, United Arab Emirates.
Victor L TyutyunnikCenter for Molecular and Cellular Biology, Moscow, Russia.
Denis V RebrikovPirogov Russian National Research Medical University, Moscow, Russia.
Dmitriy M ChudakovShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.
Olga V BritanovaShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T cell receptor (TCR) repertoire analysis provides crucial insight into the maturation of the adaptive immune system. In this study, we examined the diversity and structure of TCRβ repertoire in the sorted naïve CD4

Indexed as

Receptors, Antigen, T-Cell, alpha-betaT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsAdolescentAdultAge FactorsCD8-Positive T-LymphocytesChildChild, PreschoolComplementarity Determining RegionsFemaleFetal BloodHumansInfantInfant, NewbornMaleComplementarity Determining RegionsReceptors, Antigen, T-Cell, alpha-betaCD4+CDR2–MHC interactionsnaïve CD8+TCR repertoireTreg lymphocytesumbilical cord blood

Identifiers

PMID41958674
PMCPMC13057321

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.