Evidence map›Paper›PMID 41958672›Full record

ReviewFrontiers in immunology2026

First review of chronic granulomatous disease in Palestine: clinical and genetic characteristics.

Fatima Az-Zahra Thawabteh, Sedrah Abu Rmilah, Aya Siaj, Rawan Abu Khdair, Rabee Adwan

Erratum issuedAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Fatima Az-Zahra Thawabteh *Medical Research Club, Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Sedrah Abu Rmilah *Medical Research Club, Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Aya Siaj *Medical Research Club, Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Rawan Abu Khdair *Medical Research Club, Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Rabee AdwanInfectious Diseases Specialist, Al-Makassed Hospital, East-Jerusalem, Palestine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic granulomatous disease (CGD) is an inborn error of immunity caused by genetic defects in the nicotinamide adenine dinucleotide phosphate oxidase complex, resulting in recurrent severe infections and excessive inflammatory responses. CGD is inherited in X-linked recessive and autosomal recessive patterns. X-linked variants occur in the Results: This study analyzed data from 14 CGD patients across 12 families using functional, molecular, and genetic approaches. Among the patients, 11 (78.6%) had autosomal recessive inheritance, and 3 (21.4%) had X-linked recessive inheritance. The most common variants were in the Conclusion: This study aims to increase awareness among Palestinian healthcare providers and encourage early consideration of CGD in patients with recurrent infections, even in late childhood.

Indexed as

Granulomatous Disease, ChronicAdolescentArabsChildChild, PreschoolConsanguinityFemaleGenes, RecessiveGenetic Predisposition to DiseaseHumansInfantMaleMiddle EastMutationNADPH Oxidase 2NADPH OxidasesNADPH Oxidase 2NADPH Oxidaseschronic granulomatous diseaseclinical characteristicsgeneticsimmunodeficiencylymphadenopathyPalestine

Identifiers

PMID41958672
PMCPMC13058743

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.