Evidence map›Paper›PMID 41958506›Full record

ReviewJournal of medicine and life2026

Ethical and management dilemmas in the care of the newborn at the limit of viability: a narrative review.

Claudiu Voic, Laura Georgiana Caravia, Alina Maria Borcan, Ioana Maria Toplicean, Madalina Timircan, Zoran Laurentiu Popa, Cezara Maria Mureşan, Melinda Ildiko Mitranovici, Elene Bernad

Abstract readReview
In one paragraph

Review in Journal of medicine and life, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Claudiu VoicDoctoral School, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
Laura Georgiana CaraviaDivision of Cellular and Molecular Biology and Histology, Department of Morphological Sciences, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Alina Maria BorcanDepartment of Microbiology, Prof. Dr. Matei Balș National Institute for Infectious Diseases, Bucharest, Romania.
Ioana Maria TopliceanDepartment of Biology-Chemistry, Faculty of Chemistry, Biology, Geography, West University of Timisoara, Timisoara, Romania.
Madalina TimircanDepartment of Obstetrics and Gynecology, Faculty of Medicine, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
Zoran Laurentiu PopaDepartment of Obstetrics and Gynecology, Faculty of Medicine, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
Cezara Maria MureşanDepartment of Obstetrics and Gynecology, Faculty of Medicine, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
Melinda Ildiko MitranoviciDoctoral School of Medicine and Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Targu Mures, Romania.
Elene BernadDepartment of Obstetrics and Gynecology, Faculty of Medicine, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are variations among healthcare providers regarding the gestational age considered the threshold of viability. Currently, the World Health Organization sets the lower limit of viability at 22 weeks of gestation, or a birth weight of 500 g, or a birth length of 25 cm. Neonates are not autonomous. The present study aimed to evaluate the factors involved in healthcare professionals' management decisions in cases of neonates born at the margins of viability. A narrative review was conducted, including articles published between 2005 and 2025. We included 55 manuscripts and used the SANRA quality scale for assessment. The various approaches currently used worldwide raise concerns about their potential impact on the quality of care provided to these infants. We explored survey-based evidence regarding perceptions of the limit of viability and therapeutic decisions that raise ethical issues. The lack of coherent national guidelines and legislation represents an important burden for our healthcare system. Clinicians are faced with a dilemma regarding the correct management of infants at the limit of viability: whether to prolong treatment despite possible neurological impairment or to indicate discontinuation of treatment. Prenatal counseling for parents before delivery, along with a multidisciplinary approach, is required.

Indexed as

Fetal ViabilityEthical DilemmasGestational AgeHumansInfant, NewbornCPAP, continuous positive air pressuredecision-makingethical dilemmashealthcare professionalsICR, intact cord resuscitationISUOG, International Society of Ultrasound in Obstetrics and GynecologyIUGR, intrauterine growth restrictionlimit of viabilityNICU, Neonatal Intensive Carepreterm infantsTOP, Termination of pregnancy

Identifiers

PMID41958506
PMCPMC13059479

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.