Evidence map›Paper›PMID 41958493›Full record

ArticleJournal of global infectious diseases

The Right Patient at the Right Place: A Quality Improvement Initiative Implementing Safe Dehospitalization of Patients Using Parenteral Antimicrobial Therapy.

Priscila Martini Bernardi Garzella, Thais Galoppini Felix, Nancy Oliveira Dos Santos, Lital Moro Bass, Leonardo Henrique Fiuza de Meireles, Caroline Pimenta Nunes, Ancelmo Honorato Ferraz de Sousa, Carlos Eduardo Santa Cruz Vieira, Daniela Nóbrega, Suellen Moniz and 12 more

Abstract read
In one paragraph

Article in Journal of global infectious diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Priscila Martini Bernardi GarzellaEscritório de Excelência, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Thais Galoppini FelixDepartamento de Consultoria e Gestão, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Nancy Oliveira Dos SantosEscritório de Excelência, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Lital Moro BassEscritório de Excelência, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Leonardo Henrique Fiuza de MeirelesEscritório de Excelência, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Caroline Pimenta NunesDepartamento Financeiro, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Ancelmo Honorato Ferraz de SousaDepartamento Financeiro, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Carlos Eduardo Santa Cruz VieiraHospital Municipal Vila Santa Catarina, São Paulo, Brazil.
Daniela NóbregaHospital Municipal Vila Santa Catarina, São Paulo, Brazil.
Suellen MonizHospital Municipal Vila Santa Catarina, São Paulo, Brazil.
Maria Aparecida MachadoHospital Municipal Vila Santa Catarina, São Paulo, Brazil.
Fabiano Isidio de LimaHospital Municipal Vila Santa Catarina, São Paulo, Brazil.
Maria Fernanda TrindadeHospital Municipal Vila Santa Catarina, São Paulo, Brazil.
Beatrice Sampaio Dos Santos BarrosHospital Municipal Vila Santa Catarina, São Paulo, Brazil.
Ana Claudia Mallet Souza RamosHospital Municipal Vila Santa Catarina, São Paulo, Brazil.
Priscilla Santini RamalhoHospital Municipal Vila Santa Catarina, São Paulo, Brazil.
Renata Maria CabralHospital Municipal Vila Santa Catarina, São Paulo, Brazil.
Maria de Fátima Ferreira CotaHospital Municipal Vila Santa Catarina, São Paulo, Brazil.
Karina Suzane Pereira SchapowalHospital Municipal Vila Santa Catarina, São Paulo, Brazil.
Fabiana RollaHospital Municipal Vila Santa Catarina, São Paulo, Brazil.
Claudia Garcia de BarrosEscritório de Excelência, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Sebastian VernalEscritório de Excelência, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Infection prevention programs promote a set of recommendations for rational antimicrobial management, encouraging outpatient parenteral antimicrobial therapy (OPAT) or step-down transitions to oral administration, when possible. However, proper selection of the right patient is critical for safe dehospitalization. The aim of the study was to report on implementing an outpatient antimicrobial management project using an improvement science framework. Methods: A case report assessing a quality improvement initiative implementing an antimicrobial management project, DESOSP, in a Brazilian public tertiary hospital from July 2022 to June 2023. The intervention was implemented using a Breakthrough Series model, including plan-do-study-act cycles to promote OPAT and oral antimicrobial therapy (OAT) transitions. Clinical assistance outcomes were assessed from October 2022, including the dehospitalization rate of patients using antimicrobials in compliance with the eligibility criteria, the mean length of stay (MLS) of selected patients, and the hospital admission turnover rate. In addition, we used the financial data of OAT cases as a sample to estimate savings. Results: After 9 months, DESOSP increased the dehospitalization rate of eligible patients from 70% to 91%. The MLS of these patients dropped from 4.2 to 2.8 days. Turnover rate increased from 0.5 to 0.9. The readmission rates of patients receiving antibiotic therapy discharged for the same pathology within 30 days were not modified. Considering the OAT sample, we estimated savings of USD$76,949.86 (return on investment of 201.2%). Conclusion: Promoting a safe, structural, and systematic process, training, and engaging clinical teams seems feasible and valuable for promoting stewardship recommendations in the public healthcare system.

Indexed as

Anti-infective agentshealth servicespatient dischargequality improvementvalue-based health care

Identifiers

PMID41958493
PMCPMC13061150

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.