Evidence map›Paper›PMID 41958013›Full record

ArticleJournal of biological rhythms2026

Circadian Rhythms Time Seizure Severity in

Mariam Huertas-Radi, Adam A Bradlaugh, Richard A Baines

Abstract read
In one paragraph

Article in Journal of biological rhythms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mariam Huertas-RadiDivision of Neuroscience, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.ORCID 0009-0005-8665-8595
Adam A BradlaughDivision of Neuroscience, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.ORCID 0000-0001-7442-324X
Richard A BainesDivision of Neuroscience, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.ORCID 0000-0001-8571-4376

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is established that epilepsy patients can exhibit 24-h rhythms in seizure severity and occurrence. While the pathways underlying seizure rhythmicity remain poorly understood, it seems likely that a contribution from the biological clock is involved. A better understanding of any such contribution may translate to better treatments. Here, the influence of the 24-h circadian rhythm on seizure activity in

Indexed as

Circadian RhythmDrosophila melanogasterSeizuresAnimalsCircadian ClocksDarknessDisease Models, AnimalDrosophila ProteinsFemaleLightMaleMutationPeriod Circadian ProteinsPhotoperiodDrosophila ProteinsPeriod Circadian Proteinsbimodal rhythmcircadian rhythmsDrosophilaperiodseizure severityvortex assay

Identifiers

PMID41958013
PMCPMC13342475

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.