ArticleAnnals of African medicine2026
Role of Renal Doppler and Shearwave Elastography in Diabetic Nephropathy.
Article in Annals of African medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundDiabetic nephropathy is a leading cause of chronic kidney disease and end-stage renal failure worldwide. Early detection of renal microvascular and parenchymal changes is crucial for timely intervention and risk stratification.
objectivesThe objective is to evaluate the diagnostic utility of renal Doppler ultrasonography and shearwave elastography (SWE) in detecting and staging diabetic nephropathy, and to assess their correlation with biochemical markers of renal function. MATERIALS AND
methodsThis prospective cross-sectional study included adult patients with type 2 diabetes mellitus, categorized based on albuminuria stages. Renal resistive index and pulsatility index were measured using Doppler ultrasound, while renal cortical stiffness was quantified using point SWE. Findings were correlated with estimated glomerular filtration rate (eGFR), serum creatinine, and urinary albumin-creatinine ratio.
resultsIncreased renal cortical stiffness and elevated Doppler indices were observed in patients with microalbuminuria and overt nephropathy compared to normoalbuminuric diabetics. SWE showed a strong inverse correlation with eGFR and a positive correlation with urinary albumin levels. Combined use of Doppler and elastography improved early detection of subclinical nephropathy with high diagnostic sensitivity.
conclusionRenal Doppler and SWE are valuable non-invasive tools for early identification and functional assessment of diabetic nephropathy. Their integration into routine screening may enhance early detection, staging, and monitoring of renal involvement in diabetic patients.
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