SynthesisInternational journal of cancer2026
At what age should people with obesity start colorectal cancer screening?
Synthesis in International journal of cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The incidence of obesity and early-onset colorectal cancer (CRC) has rapidly increased in recent decades. We estimated CRC risk differences by body mass index (BMI) and derived corresponding BMI-specific CRC screening initiation ages across multiple countries, to help refine the timing of CRC prevention. We based our analyses on population-level CRC incidence data from the GLOBOCAN database (2022) and risk estimates from a meta-analysis of six cohort studies. The analysis included adults aged 30 to 60 years from six countries: United States, Canada, Germany, France, United Kingdom, and Italy. Individuals with overweight were used as the reference category, reflecting the average BMI of adults eligible for screening in these countries. Risk-adapted screening initiation ages were defined as the ages at which individuals with obesity reached the same 5-year cumulative CRC risk as those with overweight at ages 45 and 50 (aCR
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