ArticleMicrobial cell factories2026
Lecanicillium aphanocladii-derived copper oxide nanoparticles as a green nano-fungicide enhancing molecular and antioxidant defense against fusarium wilt in potato.
Article in Microbial cell factories, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundUtilizing fungal metabolic processes for the eco-friendly synthesis of nanomaterials has arisen as a sustainable substitute for chemical manufacturing. To the best of our knowledge, this is the first report describing the mycosynthesis of bioactive CuONPs using Lecanicillium aphanocladii and evaluating their efficacy against potato Fusarium wilt.
resultsHerein, CuONPs were mycosynthesized utilizing the cell-free filtrate of L. aphanocladii AUMC-16936, acting as a bio-reductant and capping agent. Characterization of mycosynthesized CuONPs confirmed the precise composition of the rod-shaped with a mean particle size of 15.24 ± 4.19 nm. The biogenic CuONPs demonstrated potent antifungal activity in vitro against Fusarium oxysporum, with 100 ppm identified as the optimal inhibitory concentration. In vivo trials, Foliar application of the mycosynthesized CuONPs (100 ppm) proved superior to soil watering, significantly mitigating Fusarium wilt severity. The treatment triggered a systemic defense response, evidenced by the upregulation of antioxidant enzymes, along with non-enzymatic indicators, leading to a marked reduction in oxidative stress markers (H2O2, MDA). Moreover, elevated expression levels of several regulatory defense genes, such as PR-1b, IbBBx24, and CHI, were noted in all plants that have been treated in comparison to infected ones.
conclusionsThe study presents a novel and interdisciplinary approach combining mycology, nanotechnology, and plant pathology to develop an eco-friendly strategy against potato Fusarium wilt.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.