Evidence map›Paper›PMID 41957740›Full record

ArticleBMC pediatrics2026

Comparison of vancomycin sensitive and resistant enterococcal infection in children.

Hacer Yakin, Bilge Acikalin, Osman Oguz Demir, Kubra Aykac, Gulsen Hazirolan, Ali Bulent Cengiz, Yasemin Ozsurekci

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hacer YakinDepartment of Pediatric Infectious Diseases, Hacettepe University, Ankara, Turkey.
Bilge AcikalinDepartment of Pediatrics, Hacettepe University, Ankara, Turkey.
Osman Oguz DemirDepartment of Pediatric Infectious Diseases, Hacettepe University, Ankara, Turkey.
Kubra AykacDepartment of Pediatric Infectious Diseases, Hacettepe University, Ankara, Turkey.
Gulsen HazirolanDepartment of Medical Microbiology, Hacettepe University, Ankara, Turkey.
Ali Bulent CengizDepartment of Pediatric Infectious Diseases, Hacettepe University, Ankara, Turkey.
Yasemin OzsurekciDepartment of Pediatric Infectious Diseases, Hacettepe University, Ankara, Turkey. yas.oguz99@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnterococcal infections are an increasing concern in pediatric healthcare due to their association with hospital-acquired infections and antimicrobial resistance. This study compared vancomycin-resistant (VRE) and vancomycin-sensitive Enterococcus (VSE) infections in children.

methodsMedical records of pediatric patients with VRE or VSE infections at Hacettepe University Children’s Hospital between 2014 and 2023 were retrospectively reviewed. Demographic, clinical, and microbiological data were analyzed.

resultsOf 181 isolates, 24.3% were VRE. VRE infections were linked to immunodeficiency, renal disease, prior transfusion, inotropic support, and broad-spectrum antibiotic exposure. Bacteremia predominated in both groups. VRE isolates showed multidrug resistance but remained susceptible to linezolid and daptomycin. Mortality and treatment duration were higher in VRE cases. Immunodeficiency and inotropic support predicted 30-day mortality.

conclusionVRE infections in children are associated with prolonged therapy, multidrug resistance, and higher mortality, emphasizing the importance of early detection and rational antibiotic use.

Indexed as

EnterococcusGram-Positive Bacterial InfectionsVancomycin ResistanceVancomycin-Resistant EnterococciAdolescentAnti-Bacterial AgentsChildChild, PreschoolDrug Resistance, Multiple, BacterialFemaleHumansInfantMaleRetrospective StudiesVancomycinAnti-Bacterial AgentsVancomycinAntimicrobial resistanceClinical outcomesPediatric infectionsVancomycin-Resistant Enterococcus (VRE)

Identifiers

PMID41957740
PMCPMC13196230

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.