Evidence map›Paper›PMID 41957715›Full record

Observational studyBMC cardiovascular disorders2026

The impact of misdiagnosed heart failure and cardiac or extra-cardiac disease burden on the prognosis in patients with type 2 diabetes.

Nurlan B Yeshniyazov, Igor N Posokhov, Vadim V Medovchshikov, Gulnara L Kurmanalina, Dariga E Kushimova, Iliada Zh Talipova, Kulsin K Tokbayeva, Alma S Akhmetova, Bekbolat Zholdin

Abstract readObservational Study
In one paragraph

Observational study in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Nurlan B YeshniyazovWest Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Igor N PosokhovWest Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan. igor@posohov.ru.
Vadim V MedovchshikovWest Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Gulnara L KurmanalinaWest Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Dariga E KushimovaWest Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Iliada Zh TalipovaWest Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Kulsin K TokbayevaWest Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Alma S AkhmetovaWest Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Bekbolat ZholdinWest Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe examined how misdiagnosed heart failure (HF) and the burden of cardiac and extra-cardiac diseases prognostically impact 1-year outcomes (all-cause mortality, rehospitalization, and their composite) in patients with type 2 diabetes mellitus (T2DM).

methodsA retrospective analysis of a prospective observational cohort study was performed. This study included 1008 patients with T2DM. Misdiagnosis of HF was defined as the difference between the diagnosis of HF contained in the primary care medical records of the patient upon admission and the final diagnosis established in the hospital at discharge. We used the MAGGIC risk score. Univariate and multivariate Cox proportional hazard models were used.

resultsIn the subgroup with misdiagnosed HF, multivariate Cox regression analysis showed that the MAGGIC noncardiac burden was the most significant predictor of the composite outcome (adjusted HR: 1.217 [1.079-1.461]; p < 0.001, and adjusted HR: 1.305 [1.119-1.561]; p < 0.001) during the 1-year follow-up.

conclusionsThis longitudinal study highlights that the misdiagnosis of heart failure, both under- and overdiagnosis, is common in T2DM patients and is associated with worse long-term outcomes, even after receiving appropriate hospital-based management.

Indexed as

Diabetes Mellitus, Type 2Diagnostic ErrorsHeart FailureAgedFemaleHumansMaleMiddle AgedPatient ReadmissionPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsComorbid riskHeart failureMAGGIC scoreMisdiagnosisOverdiagnosisType 2 diabetes mellitusUnderdiagnosis

Identifiers

PMID41957715
PMCPMC13202933

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.