ArticleBMC plant biology2026
QTL analysis uncovers the genetic architecture of resistance to chocolate spot disease caused by four Botrytis species on faba bean.
Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChocolate spot (CS), caused by Botrytis species, is a major disease constraining faba bean production worldwide. We investigated the genetic basis of resistance to four Botrytis species (B. fabae, B. cinerea, B. pseudocinerea, and B. fabiopsis) using a recombinant inbred line (RIL) population derived from the cross Mélodie/2 × ILB 938/2, which was evaluated with a detached-leaf assay.
resultsSignificant variation in disease severity was observed among parental lines and RILs for all four Botrytis species. The detached-leaf assay showed a strong correlation with a whole-plant assay conducted using a different B. fabae isolate, validating its effectiveness as a screening tool. QTL analysis identified six loci associated with response to Botrytis infection across Chr1, Chr4, and Chr6, explaining 7–11% of the total phenotypic variance. The overlapping QTLs on Chr1 conferred partial resistance to all four Botrytis species, while QTLs on Chr4 and Chr6 were specific to B. fabae. None of the other three species showed a unique QTL. Putative candidate gene analysis within QTL intervals revealed several defense-related gene families, including F-box protein, WRKY, MYB, and AP2/ERF transcription factors, and peroxidases involved in oxidative stress regulation.
conclusionThe consistency of response across species and the lack of unique responses from the non-fabae species suggests that selection for resistance to B. fabae may also select resistance to other Botrytis species. This study provides new insights into the shared and species-specific genetic architecture of Botrytis resistance in faba bean.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.