ArticleSleep & breathing = Schlaf & Atmung2026
Association of polysomnography findings of obstructive sleep apnea with non-arteritic anterior ischemic optic neuropathy manifestations.
Article in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
purposeWhile prior research suggests a relationship between obstructive sleep apnea (OSA) and non-arteritic anterior ischemic optic neuropathy (NAION), detailed associations remain unclear. This study investigated how polysomnography (PSG) parameters of OSA are associated with clinical features of acute NAION.
methodsWe conducted a retrospective analysis of 66 patients diagnosed with concurrent NAION and OSA between 2015 and 2023. Data on demographics, medical history, PSG results, ophthalmologic evaluations, and follow-up outcomes were analyzed. Univariate and multivariate linear regression analyses were performed to assess associations between OSA characteristics and NAION manifestations, adjusting for key confounders.
resultsThe cohort included 30 men and 36 women (mean age: 60 years). Comorbidities included hypertension (51.6%), dyslipidemia (43.8%), diabetes mellitus (DM; 32.8%), and cardiovascular diseases (17.2%). Seventeen patients (26.6%) were current smokers, and the mean body mass index (BMI) was 24.5 kg/m². Univariate regression revealed significant associations: Diminished visual fields were associated with older age, DM, and elevated Apnea– Hypopnea index (AHI) (p=0.01, 0.02, and 0.01 respectively); reduced visual acuity was linked to older age, increased shallow sleep, and lower oxygen saturation (p=0.03, 0.01, and 0.02, respectively). Increased peripapillary retinal nerve fiber layer (RNFL) thickness was associated with prolonged shallow sleep (p=0.01) which remained statistically significant after adjusting for age, sex, BMI, and smoking status.
conclusionPSG parameters of OSA, particularly AHI, sleep stage distribution, and oxygen saturation levels, are significantly associated with NAION clinical features. Comprehensive OSA assessment and management may help mitigate NAION risk and improve patient outcomes.
Indexed as
Identifiers
41957298What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.