ArticleEuropean journal of nuclear medicine and molecular imaging2026
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Article in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- When FDG-PET/CT reveals the tracks of fever.Clinical rheumatology · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePolyarteritis nodosa (PAN) is a rare necrotizing vasculitis of medium-sized vessels with heterogeneous presentations and a challenging diagnosis. While [18F]FDG PET/CT is established in large-vessel vasculitis, its role in PAN remains unclear. A distinctive “ant-farm” uptake pattern has recently been associated with PAN. This study assessed the diagnostic value of [18F]FDG PET/CT in PAN.
methodsPatients diagnosed with PAN who underwent [18F]FDG PET/CT between 2010 and 2025 were retrospectively included. Scans were blindly reviewed by two nuclear medicine physicians using a standardized grid. Abnormal uptakes, including the “ant-farm” pattern, were systematically recorded and correlated with clinical, biological, and histopathological data.
resultsForty-seven patients were included. Abnormal uptake was frequently found in the bone marrow (83%), lymph nodes (40%), and spleen (34%). Abnormal vascular uptake was observed in 36% of cases, predominantly in the femoral and tibial arteries. The “ant-farm” pattern was identified in 34% of patients with excellent inter-observer reproducibility (κ = 0.80). It was more frequent with recent PET/CT devices and whole-body acquisitions and was associated with higher C-reactive protein levels and fewer PAN-suggestive biopsies. Distinct uptake patterns were observed in etiologies of secondary PAN, including VEXAS syndrome.
conclusion[18F]FDG PET/CT is a valuable diagnostic tool in PAN and may also help identify secondary causes. The consistent “ant-farm” pattern may help distinguish patients with more inflammatory features, negative biopsy results and less PAN-related organ involvement.
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