Evidence map›Paper›PMID 41957155›Full record

ArticleScientific reports2026

Asthma-like bronchodilator responsiveness in patients with neuronal intranuclear inclusion disease.

Daisuke Tahara, Nao Tahara, Chisato Tamai, Akio Akagi, Yuichi Riku, Hiroaki Miyahara, Rei Kobayashi, Hisashi Okada, Michi Kawamoto, Junko Ishii and 21 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Daisuke Tahara *Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
Nao Tahara *Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
Chisato TamaiDepartment of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
Akio AkagiDepartment of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
Yuichi RikuDepartment of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
Hiroaki MiyaharaDepartment of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
Rei KobayashiDepartment of Neurology, NHO Nagoya Medical Center, Nagoya, Aichi, 460-0001, Japan.
Hisashi OkadaDepartment of Neurology, NHO Nagoya Medical Center, Nagoya, Aichi, 460-0001, Japan.
Michi KawamotoDepartment of Neurology, Kobe City Medical Center General Hospital, Kobe, Hyogo, 650-0047, Japan.
Junko IshiiDepartment of Neurology, Kobe City Medical Center General Hospital, Kobe, Hyogo, 650-0047, Japan.
Hiroki YamazakiDepartment of Neurology, Tokushima University Graduate School of Biomedical Science, Tokushima, Tokushima, 770-8503, Japan.
Takashi KurashigeDepartment of Neurology, NHO Kure Medical Center and Chugoku Cancer Center, Kure, Hiroshima, 737-0023, Japan.
Atsuhiko SugiyamaDepartment of Neurology, Chiba University, Chiba, Chiba, 260-8677, Japan.
Akiko NagaishiDepartment of Neurology, NHO Nagasaki Kawatana Medical Center, Higashisonogi, Nagasaki, 859-3615, Japan.
Katsuya NishidaDepartment of Neurology, NHO Hyogo Chuo National Hospital, Sanda, Hyogo, 669-1515, Japan.
Kazuma SugieDepartment of Neurology, Nara Medical University Hospital, Kashihara, Nara, 634-8522, Japan.
Takayasu FukudomeDepartment of Neurology, NHO Nagasaki Kawatana Medical Center, Higashisonogi, Nagasaki, 859-3615, Japan.
Kazuko HasegawaDepartment of Neurology, NHO Sagamihara National Hospital, Sagamihara, Kanagawa, 252-0392, Japan.
Hiroyuki IshiuraDepartment of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Okayama, 700-8558, Japan.
Haruki KoikeDepartment of Neurology, Saga University, Saga, Saga, 849-8501, Japan.
Takashi KasaiDepartment of Neurology, Kyoto Prefectural University of Medicine, Kyoto, Kyoto, 602-0841, Japan.
Toshiki MizunoDepartment of Neurology, Kyoto Prefectural University of Medicine, Kyoto, Kyoto, 602-0841, Japan.
Masahiro AndoDepartment of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Kagoshima, 890-8520, Japan.
Yujiro HiguchiDepartment of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Kagoshima, 890-8520, Japan.
Fumiaki TanakaDepartment of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, 236-0004, Japan.
Yuishin IzumiDepartment of Neurology, Tokushima University Graduate School of Biomedical Science, Tokushima, Tokushima, 770-8503, Japan.
Gen SobueAichi Medical University, Nagakute, Aichi, 480-1195, Japan.
Yasushi IwasakiDepartment of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
Satoru ItoDivision of Respiratory Medicine and Allergology, Department of Internal Medicine, School of Medicine, Aichi Medical University, Nagakute, Aichi, 480-1195, Japan.
Jun Sone *Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan. jsone@aichi-med-u.ac.jp.
Japanese Consortium for Neuronal Intranuclear Inclusion Disease Study (JaNIIDS) Group

Funding

Japan Society for the Promotion of Science 15K09312Japan Society for the Promotion of Science 19H03577Japan Society for the Promotion of Science 22K0983Ministry of Health, Labour, and Welfare, Japan JPMH19189624Ministry of Health, Labour, and Welfare, Japan JPMH 21445246Ministry of Health, Labour, and Welfare, Japan JPMH23819488Naito Foundation Naito memorial research grant of 2022
6 · The paper itself

Abstract

Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative condition characterized by the presence of intranuclear inclusions in neuronal and visceral cells. Patients with NIID can present respiratory symptoms; however, data on pulmonary functions in NIID are lacking. This study investigated the respiratory conditions in NIID patients diagnosed with histopathological and genetic studies. We conducted two spirometries before and after administrating the bronchodilator in NIID patients with asthmatic histories or symptoms. We statistically compared pre- and post-measured values including forced vital capacity (FVC), forced expiratory volume in one second (FEV

Indexed as

AsthmaBronchodilator AgentsNeurodegenerative DiseasesAdultAgedFemaleForced Expiratory VolumeHumansIntranuclear Inclusion BodiesMaleMiddle AgedNitric OxideSpirometryVital CapacityBronchodilator AgentsNitric OxideAsthmaAutonomic dysfunctionCoughNeuronal intranuclear inclusion diseaseNOTCH2NLCPulmonary function

Identifiers

PMID41957155
PMCPMC13223327

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.