Evidence map›Paper›PMID 41957115›Full record

SynthesisInternational journal of obesity (2005)2026

Assessing the effectiveness of healthy weight interventions in the early years of childhood: a systematic review and meta-analysis of evidence from high-income countries.

Disha Dhar, Lucy Karwatowska, Maria Sifaki, Semina Michalopoulou, Claire Stansfield, Jessica Packer, Simon J Russell

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in International journal of obesity (2005), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Disha Dhar *University College London, Great Ormond Street Institute of Child Health, London, UK. disha.dhar@ucl.ac.uk.ORCID 0009-0007-9537-8530
Lucy Karwatowska *University College London, Great Ormond Street Institute of Child Health, London, UK.
Maria SifakiUniversity College London, Institute of Epidemiology and Health Care, London, UK.
Semina MichalopoulouUniversity College London, Great Ormond Street Institute of Child Health, London, UK.
Claire StansfieldUniversity College London, Institute of Education, London, UK.
Jessica PackerUniversity College London, Great Ormond Street Institute of Child Health, London, UK.ORCID 0000-0002-3972-0318
Simon J RussellUniversity College London, Great Ormond Street Institute of Child Health, London, UK.ORCID 0000-0001-9447-1169

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly childhood represents an important opportunity for establishing lifelong health behaviours, including the maintenance of a healthy weight. Given that weight patterns established in early life often persist into adolescence and adulthood, there is an urgent need to understand whether universal interventions in early childhood are effective in preventing excess weight gain. We aimed to systematically synthesise the effects of universal healthy weight interventions for pre-school children on anthropometric outcomes.

methodsWe searched nine academic databases and included studies published from 2011 with pre-post implementation assessments of anthropometric outcomes amongst preschool children aged 5 years and under. Eligible studies included interventions that incorporated diet, physical activity, and/or behavioural change components. All studies were included in a narrative synthesis and, where possible, three-level random-effects meta-analyses were conducted to pool standardised mean differences.

resultsA total of 40 studies (n = 26,977 participants) met the inclusion criteria. The most commonly reported outcomes were BMI z-score (zBMI; k [number of studies] = 27), weight status categories (k = 19), BMI (k = 14), BMI percentiles (k = 11), body weight (k = 8), waist circumference (k = 8), skinfolds (k = 6), percentage body fat (k = 3), fat-free mass index (k = 3), and fat mass index (k = 2). The findings from the meta-analyses suggested that children receiving interventions had significantly lower zBMI (SMD [standardised mean difference] = -0.085, 95% CI -0.140, -0.029), lower waist circumference (SMD = -0.186, 95% CI -0.361, -0.011), percentage body fat (SMD = -0.159, 95% CI -0.290, -0.028) and higher fat-free mass index (SMD = 0.170, 95% CI 0.012, 0.328) compared to controls. No significant differences were found for BMI percentile. Narrative synthesis indicated limited evidence of effectiveness.

conclusionsUniversal multicomponent healthy weight interventions for preschool children in high-income countries were associated with modest but meaningful improvements in zBMI, waist circumference, percentage body fat, and fat-free mass index. These findings suggest that early childhood interventions can be effective if delivered at scale and may serve as a key element in broader childhood obesity prevention strategies.

Indexed as

Health PromotionPediatric ObesityBody Mass IndexBody WeightChild, PreschoolDeveloped CountriesExerciseFemaleHealth BehaviorHumansMaleWeight Gain

Identifiers

PMID41957115
PMCPMC13286995

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.