Evidence map›Paper›PMID 41956793›Full record

ReviewZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2026

[Advances in the construction and application of a novel liver organoid model for hepatitis B virus infection].

H Li, K H Xiang

Abstract readReviewEnglish Abstract
In one paragraph

Review in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

H LiDepartment of Microbiology and Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
K H XiangDepartment of Microbiology and Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.

Funding

National Natural Science Foundation of China 82570710Peking University Health Science Center Fund BMU2023YJ016
6 · The paper itself

Abstract

Hepatitis B virus (HBV) infection is one of the leading causes of liver cirrhosis and hepatocellular carcinoma, posing a threat to human health, yet its specific pathogenic mechanisms have not been fully elucidated. Organoid models have shown great potential in recent years due to significant limitations in existing cellular and animal models for HBV research. The construction of in vitro liver organoid models is important for better exploring HBV pathogenic mechanisms and achieving early-stage prevention and treatment. Currently, human liver organoid (HLO) models have been explored using various differentiation and culture protocols and have been confirmed to hold enormous potential in tissue development, disease model construction, personalized medicine, drug screening, and other aspects. This article briefly outlines the characteristics, differentiations, culture strategies, and applications of the emerging HLO model, thus providing a reference value for better understanding and optimizing support to HBV research.

Indexed as

Hepatitis BLiverOrganoidsAnimalsHepatitis B virusHumans

Identifiers

PMID41956793
PMCPMC13076393

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.