ArticleTherapeutic advances in respiratory disease
Contribution of social and environmental exposures to lung function decline in chronic obstructive pulmonary disease: longitudinal analysis of electronic medical records data.
Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThere is a paucity of knowledge regarding the joint and cumulative effects of multiple exposures from the physical, built, and social environments for chronic obstructive pulmonary disease (COPD) outcomes.
objectivesWe assessed the separate and joint contributions of such factors for initial lung function and annual rate of change in a clinical cohort of patients with COPD.
designRetrospective cohort study using electronic medical records.
methodsData on individuals with an ICD-10 diagnosis of COPD were extracted from the University of Alabama at Birmingham Health System (2010-2020). Analyses were restricted to those who met spirometric criteria for a COPD diagnosis (FEV
resultsThe analytic sample included 5652 patients. Social and environmental exposures differed by race (
conclusionAspects of the physical, built, and social environments affect COPD outcomes. Findings can be used in risk prediction models and for the development of tools that incorporate such exposures at the point of care for individualized disease management.
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