Evidence map›Paper›PMID 41956252›Full record

ArticleClinical medicine (London, England)2026

A multi-centre quality improvement project to assess the impact of a standardised NIV care bundle on mortality outcomes in patients with acute type 2 respiratory failure.

Christopher J Michie, Kirsty R Ward, Peter W Creber, Susie Beresford, Mark C Juniper, Rebecca Helen Mason

Abstract readMulticenter Study
In one paragraph

Article in Clinical medicine (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christopher J MichieRoyal United Hospital Bath, United Kingdom. Electronic address: chris.michie@nhs.net.
Kirsty R WardNorth Bristol Southmead Hospital, United Kingdom. Electronic address: Kirsty.ward1@nhs.net.
Peter W CreberNorth Bristol Southmead Hospital, United Kingdom. Electronic address: Peter.Creber@nbt.nhs.uk.
Susie BeresfordHealth Innovation West of England, United Kingdom. Electronic address: susie.beresford@nhs.net.
Mark C JuniperGreat Western Hospital, United Kingdom. Electronic address: mark.juniper@nhs.net.
Rebecca Helen MasonRoyal United Hospital Bath, United Kingdom. Electronic address: rebeccamason2@nhs.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evidence for non-invasive ventilation (NIV) is clear; however, real-world outcomes fall short of those demonstrated by clinical trials. We developed a five-step care bundle in line with BTS quality standards to standardise management and guide clinicians through the first few hours of NIV care. This was combined with staff training initiatives. The project aimed to reduce acute NIV mortality to 10%. Although this target was not met, the project delivered a 7% reduction in mortality from 28% to 21%, equating to 143 fewer deaths in 2023 compared to 2022. The project also delivered increased staff confidence. Through this project we have demonstrated that early, effective NIV, in appropriate patients, delivered in a standardised way by confident and competent staff, improves outcomes.

Indexed as

Noninvasive VentilationPatient Care BundlesQuality ImprovementRespiratory InsufficiencyAcute DiseaseAgedFemaleHumansMaleAcuteBTSCare bundleCOPDMortalityNCEPODNeuromuscular diseaseNIVObesity hypoventilationQIRespiratory

Identifiers

PMID41956252
PMCPMC13156728

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.