Evidence map›Paper›PMID 41954865›Full record

ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2026

Efficacy of Multifocal Spectacles for Myopia Control in Pre-myopic Children: A Multicentre Real-world Study.

Jing Rao, Qizhi Zhou, Yongchuan He, Jianhua Li, Zhiquan Wang, Xiao Chen, Qin Wang, Yi Kuang, Yuanyuan Tang, Quanlan Li and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Spectacle lenses for control of myopia progression in children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jing RaoAier Eye Hospital, Jinan University, Guangzhou, China.
Qizhi ZhouAier Eye Hospital, Jinan University, Guangzhou, China.
Yongchuan HeAier Eye Hospital, Jinan University, Guangzhou, China.
Jianhua LiAier Eye Hospital, Jinan University, Guangzhou, China.
Zhiquan WangChongqing Aier Eye Hospital, Chongqing, China.
Xiao ChenAier Eye Hospital, Jinan University, Guangzhou, China.
Qin WangChongqing Aier Eye Hospital, Chongqing, China.
Yi KuangChongqing Eye and Vision Care Hospital, Aier Eye Hospital Group, Chongqing, China.
Yuanyuan TangChongqing Eye and Vision Care Hospital, Aier Eye Hospital Group, Chongqing, China.
Quanlan LiChongqing Aier Eye Hospital, Chongqing, China.
Shenghui FengChongqing Aier-Mega Eye Hospital, Aier Eye Hospital Group, Chongqing, China.
Jiwen YangAier Eye Hospital, Jinan University, Guangzhou, China. yangjiwen1975@vip.163.com.

Funding

the Xiang Jiang Philanthropy Fund KY25028
6 · The paper itself

Abstract

purposeTo evaluate the efficacy of multifocal (MF) spectacles, compared with single-vision (SV) spectacles, in controlling myopia progression and delaying myopia onset amongst Chinese children with pre-myopia (spherical equivalent [SE] ≤ +0.75 and >-0.50 D).

methodsA multicentre retrospective case-control study was conducted, with baseline characteristics balanced using propensity score matching (PSM). The participants underwent spherical equivalent refraction (SE) and axial length (AL) measurements. Primary outcomes included SE and AL progression at 6 and 12 months, as well as the 1-year cumulative incidence of myopia (SE ≤ -0.50 D).

resultsA total of 1501 participants (mean age: 8.60 ± 2.26 years; mean SE: 0.00 ± 0.37 D) were included in the analysis, comprising 835 in the MF group and 666 in the SV group. After 12 months, MF spectacles slowed SE progression (difference: -0.35 ± 0.63 D; p < 0.001) and AL elongation (difference: 0.23 ± 0.27 mm; p < 0.001) significantly, compared with the SV group. The proportion of children with rapid myopia progression was significantly lower in the MF group (SE progression > 0.50 D: 20.8% vs. 45.1%, χ

conclusionThis large-scale, multicentre study demonstrated that MF spectacles effectively slow SE progression and AL elongation and delay myopia onset in pre-myopic children. Despite the inherent limitations of retrospective designs relative to randomised controlled trials, the findings provide strong real-world evidence supporting the potential of MF spectacles as an effective, non-pharmacologic intervention for pre-emptive myopia control.

Indexed as

EyeglassesMyopiaRefraction, OcularVisual AcuityCase-Control StudiesChildDisease ProgressionFemaleFollow-Up StudiesHumansMaleRetrospective StudiesTreatment OutcomeAxial length elongationMultifocal spectaclesOnset of myopiaPre-myopia, Spherical equivalent progression

Identifiers

PMID41954865
PMCPMC13369626

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.