Evidence map›Paper›PMID 41954807›Full record

ReviewCurrent pain and headache reports2026

Efficacy and Risks of Intradiscal Electrothermal Therapy (IDET) for Treatment of Low Back Pain: A Narrative Review.

Adam Litch, Austin Thomassen, Sanjana Sudini, Ahmed I Anwar, Kalob M Broocks, Zachary R Palowsky, Shahab Ahmadzadeh, Azem A Chami, Sahar Shekoohi, Alaa Abd-Elsayed and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Adam LitchSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
Austin ThomassenSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
Sanjana SudiniSchool of Medicine, University of Alabama at Birmingham, Birmingham, USA.
Ahmed I AnwarSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
Kalob M BroocksSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
Zachary R PalowskyDepartment of Anesthesiology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, 71103, USA.
Shahab AhmadzadehDepartment of Anesthesiology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, 71103, USA.
Azem A ChamiDepartment of Anesthesiology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, 71103, USA.
Sahar ShekoohiDepartment of Anesthesiology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, 71103, USA. sahar.shekoohi@lsuhs.edu.
Alaa Abd-ElsayedDepartment of Anesthesiology, University of Wisconsin, Madison, WI, USA.
Alan D KayeDepartments of Anesthesiology and Pharmacology, Toxicology, and Neurosciences, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewChronic low back pain, particularly discogenic pain, remains challenging to treat effectively due to complex underlying mechanisms and variability in patient response. Intradiscal Electrothermal Therapy (IDET) has emerged as a minimally invasive intervention to alleviate discogenic back pain through targeted thermal denaturation of nociceptive nerve fibers and collagen remodeling within the intervertebral disc. The present investigation critically examines existing literature to assess efficacy, safety profile, optimal patient selection criteria, and relative effectiveness compared to alternative minimally invasive treatments such as nucleoplasty and radiofrequency annuloplasty. RECENT

findingsWhile several randomized controlled trials and meta-analyses suggest IDET provides moderate short-term relief, some studies highlight significant placebo effects and question its long-term efficacy. Notably, careful patient selection, guided by clinical presentation and diagnostic imaging, emerges as a critical factor influencing outcomes. This review addresses potential complications, including rare but serious conditions like cauda equina syndrome and discitis. Emerging techniques such as biacuplasty and radiofrequency annuloplasty are also discussed, contextualizing IDET among other minimally invasive thermal procedures. Further research with rigorous methodological standards and consistent patient criteria is necessary to clarify the clinical utility of IDET and identify the patient populations most likely to benefit from this intervention.

Indexed as

Electric Stimulation TherapyIntervertebral DiscLow Back PainHumansTreatment OutcomeChronic Pain ManagementCollagen RemodelingDiscogenic Low Back PainIntradiscal Electrothermal TherapyMinimally Invasive ProceduresPatient SelectionThermal Annuloplasty

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.