ArticleCancer chemotherapy and pharmacology2026
Why are we still using cisplatin? : Rationale for the continued use of cisplatin in oncology.
Article in Cancer chemotherapy and pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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0 citing papers in PubMed.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although numerous novel cancer therapies have been introduced over the past five decades, cisplatin remains central to curative treatment for several major cancers, including testicular, ovarian, lung, and head and neck malignancies. The persistence of cisplatin use, despite its well-documented and often severe toxicities, constitutes a critical and unsolved paradox in oncology. Here, we examine this paradox by analyzing the economic, clinical, biological, and chemical factors that have entrenched cisplatin’s role and delayed its replacement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.