Evidence map›Paper›PMID 41954693›Full record

ArticleInternal and emergency medicine2026

Age differences in symptom burden of patients with advanced cancer admitted to an acute palliative care unit.

Sebastiano Mercadante, Yasmine Grassi, Sofia Settepani, Alessio Lo Cascio, Alessandra Casuccio

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Article in Internal and emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sebastiano MercadanteMain Regional of Supportive/Palliative Care, La Maddalena Cancer Center, Via San Lorenzo 312, 90146, Palermo, Italy. terapiadeldolore@lamaddalenanet.it.ORCID http://orcid.org/0000-0001-9859-6487
Yasmine GrassiMain Regional of Supportive/Palliative Care, La Maddalena Cancer Center, Via San Lorenzo 312, 90146, Palermo, Italy.
Sofia SettepaniMain Regional of Supportive/Palliative Care, La Maddalena Cancer Center, Via San Lorenzo 312, 90146, Palermo, Italy.
Alessio Lo CascioMain Regional of Supportive/Palliative Care, La Maddalena Cancer Center, Via San Lorenzo 312, 90146, Palermo, Italy.
Alessandra CasuccioMain Regional of Supportive/Palliative Care, La Maddalena Cancer Center, Via San Lorenzo 312, 90146, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to assess the differences in the pattern of symptoms and their changes after a comprehensive palliative care treatment in older patients in comparison with adults, who were admitted to an acute palliative care unit (APCU). Patients were categorized into three age ranges: adults (< 65 years, group A), old (65-74 years, group O), very old (75-84 years, group OO). The following parameters were collected: general characteristics, recent anticancer treatments, on/off treatment, previous care setting, Edmonton Symptom Assessment Scale (ESAS) and the Memorial Delirium Assessment Scale (MDAS), opioid doses, expressed as oral morphine equivalents (OME). Five-hundred-and-twenty patients were surveyed. Older patients had a lower Karnofsky level, were discharged on-therapy in a lower number of cases, and had a lower overall survival. The age-related differences in pain and dyspnea intensities recorded at admission, were nullified after a comprehensive palliative care treatment. Lower doses of opioids were effective. The APCU's consistency and the expertise of its team contributed to improved outcomes of the elderly.

Indexed as

Acute palliative care unitAgeCancerOpioidsPain

Identifiers

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.